An observational study in Disorders of Synovium, Multiple Sites, Disorders of Subchondral Bone, Multiple Sites and Disorders of Cartilage, Hand Joints, sponsored by Federal University of São Paulo. Completed. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-11-22.
Sponsored by Federal University of São Paulo · Observational
The purpose of this study is to establish the normality of sonographic synovial measures in joints more affected in rheumatoid arthritis patients and establish, in those joints, a sonographic value of synovium predictive of rheumatoid arthritis.
Rheumatoid arthritis (RA) is a chronic inflammatory, systemic and auto-imune disorder affecting primarily the joints. In RA, inflammatory synovium causes destruction of cartilage, erosion of the adjacent bone and ultimately loss of function of the affected joint. Newer imaging techniques, such as ultrasound (US), have shown promise in evaluation of RA. Many US scoring system have been used to classify and quantify the synovium, effusion, erosion and cartilage for assessing and monitoring AR. However, its use is considered problematical because there are very few data on normal joints and, at this point, there is no clear definition of excess amount of synovium in normal people.
3,554 studies on the registry are indexed under Arthritis; 317 are open to participants now.
This study's enrollment of 190 is above the median of 155 across 1,057 observational studies indexed under Arthritis.
Browse Arthritis studies →Federal University of São Paulo is the lead sponsor of 427 studies on the registry; 22 are open to participants now.
Counted across the registry records on this site, refreshed daily.
terciary care clinic (rheumatoid arthritis patients) community sample (healthy people)
Exclusion Criteria:
normal, healthy people
rheumatoid arthritis patients
No study locations are listed for this record.
This study is completed, as verified in Nov 2011. You cannot join it, but the record below documents what was studied.
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Federal University of São Paulo