An interventional study of Navigated transcranial magnetic brain stimulation in Vegetative State, Stroke and Brain Injury, sponsored by Clinical Institute of the Brain, Russia. Completed at 1 site in Russian Federation. Open to participants aged 20 Years to 85 Years. Per ClinicalTrials.gov, last updated 2013-02-15.
Sponsored by Clinical Institute of the Brain, Russia · Not applicable, Interventional, and Diagnostic
It has already been demonstrated that mental imagining of the complex motor act, such as limb lifting, can evoke the activation of the involved motor centres even if it doesn't result in movement due to paresis. Aim of the study: using the navigated brain stimulation system create a new diagnostic model for the differential diagnostics between the vegetative state and the minimally conscious state. If the investigators could get from patient the efferent motor response after a verbal command, his level of conscious should not be defined less than the minimally conscious state.
2,113 studies on the registry are indexed under Brain Injuries; 385 are open to participants now.
This study's enrollment of 6 is below the median of 48 across 1,331 interventional studies indexed under Brain Injuries.
Browse Brain Injuries studies →Clinical Institute of the Brain, Russia is the lead sponsor of 5 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Patients with the diagnosis of the vegetative state
Device: Navigated transcranial magnetic brain stimulation
Standard NBS motor mapping using the Eximia TMS stimulator, Nexstim Ltd., Finland.
MEP(motor evoked potential) parameter: latency
Time frame: within the first minute after a verbal command
MEP(motor evoked potential) parameter: amplitude
Time frame: within the first minute after a verbal command
MEP(motor evoked potential) parameter: motor threshold
Time frame: within the first minute after a verbal command
conscious state
Time frame: within the first 6 months after NBS mapping
This study is completed, as verified in Feb 2013. You cannot join it, but the record below documents what was studied.
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Clinical Institute of the Brain, Russia