An observational study in Colorectal Neoplasms, sponsored by Asan Medical Center. Status unknown at 1 site in Korea, Republic of. Open to participants aged 30 Years to 49 Years. Per ClinicalTrials.gov, last updated 2011-09-09.
Sponsored by Asan Medical Center · Observational
Current guidelines for initiating screening colonoscopies in patients younger than 50 years of age who have a first relative history of colorectal cancer are controversial. The aim of this study was to prospectively define the prevalence of colorectal adenoma 30- to 49-years-old asymptomatic subjects with a first relative history of colorectal cancer and to compare the data with controls.
Design: Single-center prospective study
Colorectal cancer screening is recommended for average-risk persons beginning at age 50. A family history of colorectal cancer is recognized as a risk factor for colorectal adenoma. However, the strength of this association is uncertain. Current guidelines for initiating screening colonoscopies in patients younger than 50 years of age who have a first relative history of colorectal cancer have proved controversial. The conflicting recommendations are partly attributable to the lack of data about the prevalence of CRC and adenomas among 30- to 49-year-old individuals with a first relative history of colorectal cancer. This prospective study will quantify the prevalence of adenomas (any size) and advanced adenomas among 30- to 49-year-old individuals undergoing their first screening colonoscopy because of a first relative history of colorectal cancer and compare the data with controls(asymptomatic subjects without a first relative history of colorectal cancer).
5,598 studies on the registry are indexed under Colorectal Neoplasms; 1,458 are open to participants now.
This study's planned enrollment of 1,000 is above the median of 250 across 1,226 observational studies indexed under Colorectal Neoplasms.
Browse Colorectal Neoplasms studies →Asan Medical Center is the lead sponsor of 562 studies on the registry; 71 are open to participants now.
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30- to 49-year-old asymptomatic subjects undergoing first screening colonoscopy because of a first relative history of colorectal cancer
Exclusion Criteria:
30- to 49-year-old asymptomatic subjects with a first relative history of colorectal cancer
prevalence of colorectal adenoma(any size)
Time frame: First screening colonoscopy
prevalence of advanced adenoma
1. Any adenoma ≥10 mm 2. Any villous component 3. High-grade dysplasia
Time frame: First screening colonoscopy
This study is status unknown, as verified in Sep 2011. You cannot join it, but the record below documents what was studied.
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Asan Medical Center