An interventional study of Control and Remote ischemic preconditioning in Aortic Valve Stenosis, sponsored by University Hospital, Angers. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2012-10-24.
Sponsored by University Hospital, Angers · Not applicable, Interventional, and Treatment
RIP-VALVE is a randomized, single blinded study that will test the hypothesis that remote ischemic preconditioning initiated before surgery reduces post-operative myocardial damage in aortic valve surgery. Infarct size will be determined by 72 hours area under curve of troponin-I.
The hypothesis tested in this research proposal is that remote ischemic preconditioning initiated immediately before aortic valve surgery reduces myocardial damage related to surgery.
985 studies on the registry are indexed under Aortic Valve Stenosis; 283 are open to participants now.
This study's enrollment of 100 is below the median of 120 across 525 interventional studies indexed under Aortic Valve Stenosis.
Browse Aortic Valve Stenosis studies →University Hospital, Angers is the lead sponsor of 464 studies on the registry; 116 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Procedure: Control
Procedure: Remote ischemic preconditioning
Deflated blood pressure cuff placed on upper arm for 30min
Blood pressure cuff placed on upper arm and inflated to 200 mmHg for 5 min and then deflated for 5 min. This cycle is initiated before aortic clamping and repeated 3 times in total
Infarct size
Infarct size as assessed by 72 hours area under curve serum troponin-I
Time frame: 72 hours
This study is completed, as verified in Oct 2012. You cannot join it, but the record below documents what was studied.
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University Hospital, Angers