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CompletedNCT01330004BPUpdated May 5, 2015

Blood Pressure Change and Outcome

An observational study in Renal Disease and High Blood Pressure, sponsored by Renal Research Institute. Completed at 1 site in United States. Open to participants aged 18 Years to 88 Years. Per ClinicalTrials.gov, last updated 2015-05-05.

Sponsored by Renal Research Institute · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
12,695
Ages
18 Years to 88 Years
Sex
All
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Study summary

Hyper- and hypotension are important predictors of survival in non-ESRD (end stage renal disease) population. In dialysis patients, however, it has been shown that higher blood pressure levels may actually be beneficial to patient outcomes. Dynamics of blood pressure evolution over time has not been previously studied in dialysis population. The investigators aim to understand how both blood pressure levels and blood pressure changes over time predict patient survival.

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Conditions studied

  • Renal Disease
  • High Blood Pressure

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In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.

This study's enrollment of 12,695 is above the median of 210 across 1,359 observational studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

Renal Research Institute is the lead sponsor of 18 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 88 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Renal Research Institute hemodialysis patients

Eligibility criteria

Inclusion Criteria:

  • Hemodialysis
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
12,695 participants (actual)

Groups and cohorts

  • Hemodialysis patients
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What researchers measure

Primary outcomes

  1. Effect size of the relation of dynamic changes of blood pressure (BP) at different ranges of BP to survival in incident hemodialysis patients.

    The ranges of blood pressure measurements in mmHg over time and the relation to patient outcomes (including survival)

    Time frame: Up to 11 years and 11 months

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Study locations

1 site
  • Renal Research Institute
    New York, New York 10128, United States
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References and documents

Publications

  • Raimann JG, Usvyat LA, Thijssen S, Kotanko P, Rogus J, Lacson E Jr, Levin NW. Blood pressure stability in hemodialysis patients confers a survival advantage: results from a large retrospective cohort study. Kidney Int. 2012 Mar;81(6):548-58. doi: 10.1038/ki.2011.426. Epub 2012 Jan 4. PubMed 22217879 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 5, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01330004
Lead sponsor
Renal Research Institute
Responsible party
Sponsor
First posted
Apr 6, 2011
Start date
Jan 1999
Primary completion
Dec 2010
Completion
Dec 2010
Last update
May 5, 2015

Study contacts

Nathan W Levin, MD
principal investigator · Renal Research Institute

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2015. You cannot join it, but the record below documents what was studied.

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