CClinicalTrials.gg
Status unknownNCT01284439Updated Jan 27, 2011

Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma

An interventional study of hydroxypropylmethylcellulose and sodium hyaluronate in Ocular Surface Disease and Glaucoma, sponsored by Mahidol University. Status unknown at 1 site in Thailand. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-01-27.

Sponsored by Mahidol University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jan 2011), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
120
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

To study effect of hydroxypropylmethylcellulose 0.3% and sodium hyaluronate 0.18% in the treatment of ocular surface disease in glaucoma patients.

02

Conditions studied

  • Ocular Surface Disease
  • Glaucoma

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03

In context

Glaucoma

1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.

This study's planned enrollment of 120 is above the median of 65 across 1,272 interventional studies indexed under Glaucoma.

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Lead sponsor

Mahidol University is the lead sponsor of 730 studies on the registry; 118 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • OSDI > or equal 20 and eye lid inflammation , meibomian gland inflammation,conjunctival injection,follicle at tarsus , positive corneal staining , tear break up time less than 8 seconds , tear volume less than 5.5 mm.

Exclusion criteria

Exclusion Criteria:

  • Age below 18 yo
  • Active infectious corneal disease
  • Post penetrating keratoplasty or glaucoma drainage device
  • Known allergy to medication
  • Lactation , Pregnant
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
120 participants (estimated)

Study arms

  • Experimental
    TearA

    Drug: hydroxypropylmethylcellulose

  • Experimental
    TearB

    Drug: sodium hyaluronate

Interventions

  • Drughydroxypropylmethylcellulose

    TearA: QID to every 2 hous , 1-2 drops per each time , duration 1 month

  • Drugsodium hyaluronate

    QID to every 2 hous, 1-2 drops per each time, duration 1 month

06

What researchers measure

Primary outcomes

  1. Ocular surface index score

    Time frame: 1 month

Secondary outcomes

  1. Eye lid inflammation, corneal staining score, tear break up time and tear volume

    Time frame: 1 month

07

Study locations

1 of 1 sites recruiting
  • Department of Ophthalmology , Siriraj Hospital
    Bangkok, Thailand
    • Assoc Prof Pinnita Tanthuvanit · Principal investigator
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 27, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01284439
Lead sponsor
Mahidol University
First posted
Jan 27, 2011
Start date
Jan 2011
Primary completion
Jan 2012 (estimated)
Completion
Feb 2012 (estimated)
Last update
Jan 27, 2011

Study contacts

AssocProf Pinnita Tanthuvanit
Contact
02-4198036
AssocProf Pinnita Tanthuvanit, MD
principal investigator · Mahidol University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2011. You cannot join it, but the record below documents what was studied.

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