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CompletedNCT01271426Updated Jan 6, 2011

Response to Ranibizumab in Polypoidal Choroidal Vasculopathy (PCV)and SNPs

An observational study in Polypoidal Choroidal Vasculopathy, sponsored by Nihon University. Completed at 1 site in Japan. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2011-01-06.

Sponsored by Nihon University · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
74
Ages
50 Years and older
Sex
All
01

Study summary

To determine whether complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2) genotypes have a pharmacogenetic effect on the treatment of polypoidal choroidal vasculopathy (PCV) with ranibizumab.

02

Conditions studied

  • Polypoidal Choroidal Vasculopathy

Keywords

  • Polypoidal Choroidal Vasculopathy
  • Ranibizumab
03

In context

Polypoidal Choroidal Vasculopathy

55 studies on the registry are indexed under Polypoidal Choroidal Vasculopathy; 5 are open to participants now.

This study's enrollment of 74 is below the median of 121 across 13 observational studies indexed under Polypoidal Choroidal Vasculopathy.

Browse Polypoidal Choroidal Vasculopathy studies →

Lead sponsor

Nihon University is the lead sponsor of 13 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

outpatients in hospital

Inclusion criteria

  • Clinical diagnosis of Polypoidal choroidal vasculopathy
  • must have injection of Ranibizumab

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
74 participants (actual)
Biospecimen retention
Samples with dna
06

What researchers measure

Primary outcomes

  1. Association of Complement Factor H and ARMS2 Genotypes with Response of Polypoidal Choroidal Vasuculopathy to Intravitral Ranibizumab

    Time frame: a month after injection

07

Study locations

1 site
  • Surugadai Nihon university hospital
    1-8-13 Kandasurugadai Chiyoda-ku, Tokyo 101-8309, Japan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 6, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01271426
Lead sponsor
Nihon University
First posted
Jan 6, 2011
Start date
Apr 2008
Primary completion
Mar 2010
Completion
Mar 2010
Last update
Jan 6, 2011
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jan 2011. You cannot join it, but the record below documents what was studied.

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