An observational study in Respiratory Distress Syndrome, Adult, sponsored by Rennes University Hospital. Completed at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-07-03.
Sponsored by Rennes University Hospital · Observational
Despite improving in the treatment of acute respiratory distress syndrome (ARDS), this affection keep an elevate rate of death. The strategy of mechanical ventilation is more and more under definite protocol, following large strength randomized studies. Although, it doesn't exist today element allowing to adjust the level of Positive End-Expiratory Pressure (PEEP) with improvement in patient's survival.
The investigators proposed in this study to determinate the level of PEEP adjust to obtain the better arterial oxygen transport (TaO2). The investigators going to conduct a physiologic, observational, none controlled study. All patients hospitalized in intensive care unit of Pontchaillou hospital with ARDS criteria and without specific exclusion criteria will be included. Primary objective is to looking for the optimum level of PEEP for TaO2.
1,619 studies on the registry are indexed under Respiratory Distress Syndrome; 319 are open to participants now.
This study's enrollment of 12 is below the median of 100 across 548 observational studies indexed under Respiratory Distress Syndrome.
Browse Respiratory Distress Syndrome studies →Rennes University Hospital is the lead sponsor of 451 studies on the registry; 51 are open to participants now.
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Patients with acute respiratory distress syndrome
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Exclusion Criteria:
Determinate the Positive End-Expiratory Pressure (PEEP) level achieving the best arterial oxygen transport (TaO2)
Time frame: 1 year
Evolution of pulmonary gas exchanges
Time frame: 1 year
Evolution of respiratory mechanism parameters
Time frame: 1 year
evolution of circulatory parameters and needs of catecholamine during the study
Time frame: 1 year
Appearance of secondary effects due to mechanical ventilation
Time frame: 1 year
This study is completed, as verified in Jul 2013. You cannot join it, but the record below documents what was studied.
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