An interventional study of Pacemaker in Left Ventricular Hypertrophy, Diastolic Dysfunction and Heart Failure, sponsored by University of Aarhus. Terminated at 1 site in Denmark. Open to participants aged 30 Years to 90 Years. Per ClinicalTrials.gov, last updated 2012-08-06.
Sponsored by University of Aarhus · Not applicable and Interventional
The purpose of this study is to compare the effect of heart rate on cardiac index in patients with or without left ventricular hypertrophy. The study will be conducted in postoperative heart surgery patients with a pacemaker.
5,701 studies on the registry are indexed under Heart Failure; 1,220 are open to participants now.
This study's enrollment of 11 is below the median of 72 across 3,736 interventional studies indexed under Heart Failure.
Browse Heart Failure studies →University of Aarhus is the lead sponsor of 1,274 studies on the registry; 183 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Group: Left ventricular hypertrophy:
Thickness of interventricular septum and posterior wall >11 mm.
Group: No left ventricular hypertrophy:
Thickness of interventricular septum and posterior wall \<11 mm.
Exclusion Criteria:
Postoperative patient with normal left ventricular size
Device: Pacemaker
Postoperative patient with left ventricular hypertrophy
Device: Pacemaker
Routine postoperative temporary pacemaker Rate change of 65-80-95-110-125 beats/second in random order at day 3-4 after operation
Cardiac index
Time frame: At heart rates 65-80-95-110-125
Mean arterial blood pressure
Time frame: At heart rates 65-80-95-110-125
Ejection fraction
Echocardiographic index of systolic function
Time frame: Heart rates of 65-80-95-110-120
Strain
Echocardiographic index of systolic function
Time frame: Heart rates of 65-80-95-110-125
S-max
Echocardiographic index of systolic function
Time frame: Heart rates of 65-80-95-110-125 beats per second
E/E'
Echocardiographic index of diastolic function
Time frame: Heart rates of 65-80-95-110-125 beats per second
E/A ratio
Echocardiographic index of diastolic function
Time frame: Heart rates of 65-80-95-110-125 beats per second
E'/A' ratio
Echocardiographic index of diastolic function
Time frame: Heart rates of 65-80-95-110-125 beats per second
Isovolumetric relaxation index
Echocardiographic index of diastolic function
Time frame: Heart rates of 65-80-95-110-125 beats per second
IVRT/IVRT'
Echocardiographic index of diastolic function
Time frame: Heart rates of 65-80-95-110-125 beats per second
End diastolic volume
Volume of left ventricle and end diastole
Time frame: Heart rates of 65-80-95-110-125 beats per second
End systolic volume
Volume of left ventricle at end systole
Time frame: Heart rates of 65-80-95-110-125 beats per second
This study is terminated, as verified in Aug 2012. You cannot join it, but the record below documents what was studied.
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University of Aarhus