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CompletedNCT01224574COAGFAIIUpdated Oct 20, 2010

To Assess the Predictive Value of D-dimer Level on the Occurrence of Cardiovascular Events

An observational study in Atrial Fibrillation, sponsored by Hopital Lariboisière. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-10-20.

Sponsored by Hopital Lariboisière · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
425
Ages
18 Years and older
Sex
All
01

Study summary

The primary aim of the study was to assess whether D-Dimer level at entry or an increase of D-Dimer level during the follow-up could predict the occurrence of subsequent cardiovascular events in patients with atrial fibrillation.

Read the detailed description

Patients will be followed-up every 4 months with clinical assessment and D-dimer blinded measurement.

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Conditions studied

  • Atrial Fibrillation

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Keywords

  • atrial fribrillation, cardiovascular events, aging, D-dimer
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In context

Atrial Fibrillation

3,870 studies on the registry are indexed under Atrial Fibrillation; 924 are open to participants now.

This study's enrollment of 425 is above the median of 300 across 1,363 observational studies indexed under Atrial Fibrillation.

Browse Atrial Fibrillation studies →

Lead sponsor

Hopital Lariboisière is the lead sponsor of 29 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with atrial fibrillation encountered in usual care

Inclusion criteria

  • atrial fibrillation

Exclusion criteria

Exclusion Criteria:

  • follow-up not possible, poor prognosis within 3 months
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
425 participants (actual)
Biospecimen retention
Samples without dna
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Study locations

1 site
  • AP HP
    Paris, France
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References and documents

Publications

  • Mahe I, Drouet L, Simoneau G, Minh-Muzeaux S, Caulin C, Bergmann JF. D-dimer can predict survival in patients with chronic atrial fibrillation. Blood Coagul Fibrinolysis. 2004 Jul;15(5):413-7. doi: 10.1097/01.mbc.0000114440.81125.bd. PubMed 15205590 ↗
  • Mahe I, Drouet L, Chassany O, Mazoyer E, Simoneau G, Knellwolf AL, Caulin C, Bergmann JF. D-dimer: a characteristic of the coagulation state of each patient with chronic atrial fibrillation. Thromb Res. 2002 Jul 15;107(1-2):1-6. doi: 10.1016/s0049-3848(02)00184-6. PubMed 12413581 ↗
  • Mahe I, Grenard AS, Joyeux N, Caulin C, Bergmann JF. Management of oral anticoagulant in clinical practice: a retrospective study of 187 patients. J Gerontol A Biol Sci Med Sci. 2004 Dec;59(12):1339-42. doi: 10.1093/gerona/59.12.1339. PubMed 15699536 ↗
  • Lafuente-Lafuente C, Mahe I, Extramiana F. Management of atrial fibrillation. BMJ. 2009 Dec 23;339:b5216. doi: 10.1136/bmj.b5216. No abstract available. PubMed 20032065 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 20, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01224574
Lead sponsor
Hopital Lariboisière
Collaborators
Ministry of Health, France
First posted
Oct 20, 2010
Start date
Jan 2001
Primary completion
Jul 2006
Completion
Jul 2007
Last update
Oct 20, 2010

Study contacts

Isabelle Mahé, MD,PhD
principal investigator · Hopital Lariboisière

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2010. You cannot join it, but the record below documents what was studied.

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