An observational study in Male Infertility, sponsored by Hillel Yaffe Medical Center. Status unknown at 1 site in Israel. Open to male participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-08-10.
Sponsored by Hillel Yaffe Medical Center · Observational
The researchers hypothesized that nonobstructive azoospermia might be associated with a reduction OF SSCs in seminiferous tubules as compared with obstructive azoospermia. Testicular sperm specimens that had been previously extracted from azoospermic patients will be paraffin embedded and stained with anti GPR-125. After antigen retrieval, the sections will be incubated with rabbit anti GPR125 followed by Cy3-conjugated anti rabbit secondary antibodies. Those found to be SSCs will be counted using light microscopy, and compared between patients with obstructive (n=11) and non-obstructive azoospermia (n=9).
2,506 studies on the registry are indexed under Infertility; 407 are open to participants now.
This study's planned enrollment of 25 is below the median of 200 across 714 observational studies indexed under Infertility.
Browse Infertility studies →Hillel Yaffe Medical Center is the lead sponsor of 301 studies on the registry; 10 are open to participants now.
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Infertile male patients treated at the Hillel Yaffe Medical Center IVF Unit
Exclusion Criteria:
Other: Biospecimen staining
Other: Biospecimen staining
The sections will be incubated with rabbit anti GPR125 followed by Cy3-conjugated anti rabbit secondary antibodies.
The sections will be incubated with rabbit anti GPR125 followed by Cy3-conjugated anti rabbit secondary antibodies.
SSCs were identified in both obstructive and nonobstructive azoospermia patients.
Time frame: One year
This study is status unknown, as verified in Aug 2010. You cannot join it, but the record below documents what was studied.
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Hillel Yaffe Medical Center