An interventional study of Hydration and Acetylcysteine in Contrast Induced Nephropathy, sponsored by Odense University Hospital. Completed at 1 site in Denmark. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-03-22.
Sponsored by Odense University Hospital · Not applicable, Interventional, and Prevention
OBJECTIVE: To evaluate the efficacy of prevention of contrast induced nephropathy in patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention.
DESIGN: Prospective study. SETTING: Three-center study Acute kidney injury was defined as a rise in creatinine >25% from baseline Serum creatinine will be measured at baseline and each day for the following 3 days and at 30 days.
Patients will be randomised to:
3,840 studies on the registry are indexed under Kidney Diseases; 500 are open to participants now.
This study's enrollment of 720 is above the median of 70 across 2,640 interventional studies indexed under Kidney Diseases.
Browse Kidney Diseases studies →Odense University Hospital is the lead sponsor of 468 studies on the registry; 109 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Hydration
Other: Hydration
Drug: Combined Acetylcystein and Sodium Bicarbonate
Drug: Sodium bicarbonate
Standard treatment + acetylcystein for 2 days
Drug: Acetylcysteine
Saline hydration
Acetylcystein tablets for 2 days
Sodium bicarbonate 500 ml followed by 100 ml/hour for 5 hours
Sodium bicarbonate 500 ml followed by 100 ml/hour for 5 hours combined with acetylcystein tablets for 2 days
Prevention of contrast induced nephropathy in STEMI patients treated with primary PCI
Rise in creatinine \>25% from baseline to day 3
Time frame: from baseline to day 3
Prevention of contrast induced nephropathy in STEMI patients treated with primary PCI
Rise in creatinine \>25% from baseline to day 30
Time frame: from baseline to day 30
This study is completed, as verified in Mar 2013. You cannot join it, but the record below documents what was studied.
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Odense University Hospital