An observational study in Rheumatoid Arthritis, sponsored by University Hospital Center of Martinique. Completed at 1 site in Martinique. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2010-12-21.
Sponsored by University Hospital Center of Martinique · Observational
Rheumatoid arthritis (RA), affects between 0.3% and 1.0% of the population, it can lead to progressive joint destruction and severe disability. To date, two RA genetic susceptibility factors have been identified: HLA-DRB1-SE (Shared epitope) and PTPN22 620W alleles. The predictive value of the alleles for diagnosis of RA was previously investigated in cohorts of caucasians patients with early unclassified arthritis that showed restrained association between RA and HLA-SE. Despite the contribution of HLA to the overall genetic risk has been estimated to range from 30% to 50%, it has never been studied in the French west-Indian population.
3,554 studies on the registry are indexed under Arthritis; 317 are open to participants now.
This study's planned enrollment of 200 is above the median of 155 across 1,057 observational studies indexed under Arthritis.
Browse Arthritis studies →University Hospital Center of Martinique is the lead sponsor of 77 studies on the registry; 20 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Residents of Martinique with at least 3 African-Caribbean grandparents
Inclusion Criteria:
Exclusion Criteria:
For the control
Inclusion Criteria:
Exclusion Criteria:
After signed written consent, all patients have a clinic exam in order to assess the presence of eligibility criteria (Patient with Rheumatoid Arthritis that fulfil the ACR criteria of diagnosis)
Also known as: Rheumatoid Arthritis, French West-Indian Patients with Rheumatoid Arthritis
Difference of distribution of HLA alleles in patients and in healthy controls
Time frame: 1 day
The association between the different HLA alleles among French West-Indian RA patients and the autoantibodies production.
Time frame: 1 day
The association between the different HLA alleles among French West-Indian RA patients and the radiological damage.
Time frame: 1 day
The association between the different HLA alleles among French West-Indian RA patients and the response to therapy
Time frame: 1 day
This study is completed, as verified in Apr 2010. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University Hospital Center of Martinique