An observational study in Stage 2-5 Chronic Kidney Disease and Predialysis, sponsored by National University of Singapore. Completed at 1 site in Singapore. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2014-11-07.
Sponsored by National University of Singapore · Observational
Vitamin D insufficiency and deficiency is common in chronic kidney disease (CKD) patients and is associated with elevated parathyroid hormone (PTH) concentration and mineral and bone disorder (MBD). There is also increasing evidence to show that these abnormalities increase cardiovascular morbidity and mortality in CKD patients. There is a need for early identification of vitamin D insufficiency/deficiency in CKD patients to prevent its long-term complications. However, the vitamin D status of CKD patients in Singapore has not been well described. The purpose of this study is to assess the vitamin D status of predialysis CKD patients in a tertiary academic teaching hospital in Singapore, and its association with parameters for MBD. Predialysis patients from the outpatient renal clinic at the National University Hospital (NUH) will be recruited into this study. Blood samples from the patients will be collected after an overnight fast to determine their serum 25(OH)D, creatinine, phosphorus, calcium, albumin and i-PTH concentrations. These parameters will be compared among patients in various stages of CKD.
3,840 studies on the registry are indexed under Kidney Diseases; 500 are open to participants now.
This study's enrollment of 196 is close to the median of 192 across 1,033 observational studies indexed under Kidney Diseases.
Browse Kidney Diseases studies →National University of Singapore is the lead sponsor of 206 studies on the registry; 52 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with stage 2-5 chronic kidney disease who are not on dialysis
Exclusion Criteria:
All patients with stage 2-5 (pre-dialysis) chronic kidney disease One-time blood draw (10 ml)
Vitamin D 25(OH)D levels
Vitamin D levels are only measured at one time point i.e. at baseline
Time frame: baseline
This study is completed, as verified in Oct 2014. You cannot join it, but the record below documents what was studied.
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National University of Singapore