An observational study in Neutropenic Fever, sponsored by National Taiwan University Hospital. Completed. Open to participants aged 18 Years to 84 Years. Per ClinicalTrials.gov, last updated 2009-12-17.
Sponsored by National Taiwan University Hospital · Observational
The soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) was an established biomarker useful for infection in non-neutropenic patients. In this study, we tested sTREM-1 in the patients with neutropenic fever. Pro-calcitonin (PCT) and C-reactive protein (CRP) were also measured. We planned to investigate and explore the role of sTREM-1 in early diagnosis of infection in patients with neutropenic fever.
Patients with hematological malignancies developed neutropenia after chemotherapy. We checked the serum level of sTREM-1 in patients with neutropenic fever. Those patients were classified to 2 groups: documented infection or low likelihood of infection. Their sTREM-1 level was measured and was compared with other biomarker such as CRP and procalcitonin. The value of sTREM-1 for diagnosis of infection in patients with neutropenic fever was thus evaluated.
151 studies on the registry are indexed under Febrile Neutropenia; 33 are open to participants now.
This study's enrollment of 75 is below the median of 131 across 56 observational studies indexed under Febrile Neutropenia.
Browse Febrile Neutropenia studies →National Taiwan University Hospital is the lead sponsor of 2,563 studies on the registry; 569 are open to participants now.
Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.
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Patients with hematological malignancy developing neutropenic fever after chemotherapy
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This study is completed, as verified in Dec 2009. You cannot join it, but the record below documents what was studied.
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National Taiwan University Hospital