An observational study in Single-nucleotide Polymorphism (SNP) for Glaucoma, sponsored by Chungnam National University. Completed at 1 site in Korea, Republic of. Open to participants aged 30 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2009-12-03.
Sponsored by Chungnam National University · Observational
A single-nucleotide polymorphism (SNP) analysis of DNA obtained from peripheral blood of the glaucoma patients and the normal control will be performed to find genetic marker for primary open angle glaucoma.
Unrelated Korean subjects who have primary open angle glaucoma were recruited in the current study. Genotyping for various SNP associated with POAG due to the linkage disequilibrium patterns is to be performed. Genotypes would be statistically compared between patients with primary open angle glaucoma and normal control subjects free of any eye diseases.
1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.
This study's enrollment of 1,224 is above the median of 103 across 454 observational studies indexed under Glaucoma.
Browse Glaucoma studies →Chungnam National University is the lead sponsor of 12 studies on the registry; 3 are open to participants now.
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patients with open angle glaucoma who visited glaocoma clinic of departemtn of Ophtalmology, Chungnam National University Hospital, Daejeon, south Korea
Exclusion Criteria:
Elevated intraocular pressure normal open angle glaucomatous optic nerve head abnormality glaucomatous visual field defect
Genetic: SNP analysis of the DNA
Normal intraocular pressure No optic disc abnormality No visual field defect No significant ocular and systemic disease
Genetic: SNP analysis of the DNA
SNP analysis of the DNA obtained from peripheral blood sample
genotyping for the SNP associated with primary open angle glaucoma
Time frame: one year
genotyping for rs7961953 and additional SNPs in TMTC2 from other linkage disequilibrium patterns
Time frame: one year
This study is completed, as verified in Dec 2009. You cannot join it, but the record below documents what was studied.
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Chungnam National University