ClinicalTrials.gg
CompletedNCT01020370Updated Nov 25, 2009

Exploratory Study to Investigate the Reparative and Regenerative Potential of Alemtuzumab in Relapsing-Remitting Multiple Sclerosis Patients Participating in the CARE MS I and MS II Studies

An observational study in Multiple Sclerosis, sponsored by Wayne State University. Completed. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2009-11-25.

Sponsored by Wayne State University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The primary goal of this study will be to explore the reparative and regenerative potential of alemtuzumab in RRMS patients who are participating in the CARE MS I and CARE MS II studies using conventional and non-conventional MRI sequences.

02

Conditions studied

  • Multiple Sclerosis

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Keywords

  • Patients with RRMS who are participating in the CARE MS I and CARE MS II
03

In context

Multiple Sclerosis

3,524 studies on the registry are indexed under Multiple Sclerosis; 668 are open to participants now.

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Lead sponsor

Wayne State University is the lead sponsor of 229 studies on the registry; 34 are open to participants now.

Of its 17 completed or terminated interventional studies of FDA-regulated products, 4 (24%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with RRMS who are participating in the CARE MS I and CARE MS II studies and are receiving either alemtuzumab or interferon beta-1a SC

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Participating in either the CARE MS I or CARE MS II studies

Exclusion criteria

Exclusion Criteria:

  • Not a participant in the CARE MS I or CARE MS II studies
05

Study design

Observational model
Cohort
Time perspective
Prospective

Groups and cohorts

  • Alemtuzumab Group
  • Interferon Beta-1a SC Group
06

What researchers measure

Primary outcomes

  1. Explore the reparative and regenerative potential of alemtuzumab in RRMS patients who are participating in the CARE MS I and CARE MS II studies

Secondary outcomes

  1. Compare the effect of alemtuzumab to interferon beta-1a SC on non-conventional MRI outcomes

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 25, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01020370
First posted
Nov 25, 2009
Last update
Nov 25, 2009

Study contacts

Omar Khan, MD
principal investigator · Wayne State University
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2009. You cannot join it, but the record below documents what was studied.

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