CClinicalTrials.gg
CompletedNCT00953264Updated Dec 15, 2017

Hormonal and Metabolic Effects of Weight Loss

An interventional study of lifestyle in Obesity, sponsored by Charite University, Berlin, Germany. Completed at 1 site in Germany. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-12-15.

Sponsored by Charite University, Berlin, Germany · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
290
Allocation
Not applicable
Ages
18 Years to 75 Years
Sex
All
01

Study summary

The investigators here propose to evaluate the hormonal and metabolic effects of weight loss, including evaluation of changes in several tissues.

02

Conditions studied

  • Obesity

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03

In context

Weight Loss

1,766 studies on the registry are indexed under Weight Loss; 277 are open to participants now.

This study's enrollment of 290 is above the median of 73 across 1,496 interventional studies indexed under Weight Loss.

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Lead sponsor

Charite University, Berlin, Germany is the lead sponsor of 836 studies on the registry; 129 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • BMI > 27 kg/m2 (adults)

Exclusion criteria

Exclusion Criteria:

  • pregnancy, breastfeeding
  • patients with:

    • heart failure
    • impaired hepatic or renal function
    • anaemia
    • disturbed coagulation
    • infection, malabsorption
    • severe hypertension
    • any other endocrine disorder
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
290 participants (actual)

Study arms

  • Experimental
    life style intervention

    Behavioral: lifestyle

Interventions

  • Behaviorallifestyle

    lifestyle intervention, including diet, physical activity and behavioral changes

06

What researchers measure

Primary outcomes

  1. hormonal and metabolic changes during weight loss

    Time frame: 6 month

07

Study locations

1 site
  • Charite
    Berlin, 12200, Germany
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 15, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00953264
Lead sponsor
Charite University, Berlin, Germany
Responsible party
Professor Joachim Spranger (Professor, Charite University, Berlin, Germany) — Principal investigator
First posted
Aug 6, 2009
Start date
Dec 2007
Primary completion
Dec 2013
Completion
Dec 2013
Last update
Dec 15, 2017

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2016. You cannot join it, but the record below documents what was studied.

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