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CompletedNCT00913354Updated Jun 4, 2009

Acupuncture Versus Placebo Acupuncture During In Vitro Fertilization (IVF) Embryo Transfer

An interventional study of Acupuncture (Carbo®) and Placebo acupuncture (Strietberger®) in Infertility, sponsored by Rigshospitalet, Denmark. Completed at 1 site in Denmark. Open to female participants aged 18 Years to 37 Years. Per ClinicalTrials.gov, last updated 2009-06-04.

Sponsored by Rigshospitalet, Denmark · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
635
Allocation
Randomized
Ages
18 Years to 37 Years
Sex
Female
01

Study summary

During IVF treatment, acupuncture at the time of embryo transfer may improve the pregnancy rate. This study aims to compare IVF pregnancy between two groups of patients that received either acupuncture or sham acupuncture (placebo)around embryo transfer

Read the detailed description

Acupuncture at the time of embryo transfer may improve the IVF pregnancy rate. This study aims to compare the IVF pregnancy between two groups of patients that undergo ivf/icsi treatment. The patients are randomized to receive either acupuncture or sham acupuncture (placebo)around embryo transfer

02

Conditions studied

  • Infertility

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Keywords

  • infertility
  • ivf
  • acupuncture
03

In context

Infertility

2,506 studies on the registry are indexed under Infertility; 407 are open to participants now.

This study's enrollment of 635 is above the median of 120 across 1,698 interventional studies indexed under Infertility.

Browse Infertility studies →

Lead sponsor

Rigshospitalet, Denmark is the lead sponsor of 1,017 studies on the registry; 183 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 37 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • infertility
  • below 38 years
  • ivf or icsi treatment
  • fresh embryo transfer cycle
  • no more than two earlier embryo transfers with "fresh" embryos
  • embryo transfer on day 2 or 3 after oocyte aspiration, single or double embryo transfer

Exclusion criteria

Exclusion Criteria:

  • Frozen embryo transfer
  • oocyte donation
  • other "alternative" treatment during the cycle
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
635 participants (actual)

Study arms

  • Experimental
    1

    30 minutes of acupuncture just before and just after embryo replacement

    Device: Acupuncture (Carbo®)

  • Placebo comparator
    2

    Sham acupuncture for 30 minutes just before and just after embryo transfer

    Device: Placebo acupuncture (Strietberger®)

Interventions

  • DeviceAcupuncture (Carbo®)

    The acupuncture points were chosen according to traditional Chinese medicine and included DU20, M29, KS6, Mp8, and Le3 before embryo transfer and DU20, Co4, Mp10, M36, and Mp6 after embryo transfer.

    Also known as: Acupuncture needles: Carbo® needle,Acupharma A/S.

  • DevicePlacebo acupuncture (Strietberger®)

    The acupuncture points were the same as in the true acupuncture group, namely DU20, M29, KS6, Mp8, and Le3 before embryo transfer and DU20, Co4, Mp10, M36, and Mp6 after embryo transfer. Sham acupuncture needles used were the validated Strietberger® placebo-needle from the company, Asia Med. The needle is not fixed inside the copper handle and its tip is blunt. When the needle touches the skin it moves inside the handle and appears to be shortened. A pricking sensation is felt by the patient, simulating the puncturing of the skin. Developed by dr. Konrad Streitberger.

    Also known as: Sham acupuncture needles: Strietberger® placebo-needle, Asia Med.

06

What researchers measure

Primary outcomes

  1. Clinical pregnancy rate

    Time frame: 2005-2008

07

Study locations

1 site
  • The Fertility Clinic, Copenhagen University Hospital, Denmark
    Copenhagen, 2100, Denmark
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 4, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00913354
Lead sponsor
Rigshospitalet, Denmark
First posted
Jun 4, 2009
Start date
Nov 2005
Primary completion
Mar 2007
Completion
Mar 2009
Last update
Jun 4, 2009

Study contacts

Dorthe Andersen, Study nurse
principal investigator · The Fertility Clinic, Copenhagen University Hospital Rigshospitalet

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2005. You cannot join it, but the record below documents what was studied.

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