Comparison Study of Topical Acne Regimens

• Subjects and/or subjects' legal guardians who understand and are willing to sign an Informed Consent Form, an Assent Form if indicated, and a HIPAA Authorization Form.
• Subjects who have received the permission of a parent or guardian to participate in this study or cannot be classified as a minor, under the age of 18 years.
• Male and female subjects between the ages of 13 and 45 years and in generally good health, as determined by a Medical History Form.
• Subjects with moderately-severe acne vulgaris of the face and neck as determined and defined by baseline lesion counts (see Definition: Acne Severity above).
• Subjects who have completed a Medical History Form.
• Subjects who have not used oral acne medications for 1 month prior to start of study, and topical acne medications 1 week prior to start of study.
• Subjects who agree not to use any acne medication during the study except for the test materials given to them.
• Subjects who agree not to use any make-up that contains acne treatment additives, such as benzoyl peroxide, salicylic acid or retinol.
• Subjects who are willing to be photographed and video-recorded during study visits and willing to sign photographic release forms.
• Subjects who exhibit dependability and intelligence in following directions.

Exclusion Criteria:

• Subjects who are pregnant or lactating.
• Subjects with known allergies to cosmetic, toiletry, or acne treatment products.
• Subjects who are sensitive to any of the ingredients in the test articles.
• Subjects who have participated in a facial treatment study within 3 weeks of study initiation.
• Subjects exhibiting acute or chronic dermatological, medical, and/or physical conditions which would preclude application of the test materials and/or influence the outcome of the study.
• Subjects who are unable to sit quietly for 15 minutes to acclimate to ambient temperature and humidity conditions in the laboratory.
• Male subjects who do not have a full beard.
• Subjects who cannot stop usage of oral acne mediation 1 month prior to study start, and topical acne medications 1 week prior to study start.
• Subjects taking routine high dosage anti-inflammatory medications (aspirin, ibuprofen).
• Subjects who must use oral corticosteroids and/or oral immunosuppressive drugs (steroid inhalers or decongestant nose drops and/or eye drops are permitted).
• Any condition for which the Investigator determines that the subject could be placed under undo risk.