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Status unknownNCT00902057Updated May 14, 2009

Desmopressin for Bleeding Related to Low Body Temperature

A Phase 4 interventional study of desmopressin and desmopressin in Hypothermia Induced Impairment of Primary Haemostasis, sponsored by The University of Hong Kong. Status unknown at 1 site in China. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2009-05-14.

Sponsored by The University of Hong Kong · Phase 4, Interventional, and Treatment

The sponsor has not verified this record recently (last verified May 2009), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Phase 4
Study type
Interventional
Enrollment
48
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
All
01

Study summary

To study, with a prospective randomised controlled design, whether the subcutaneous administration of the haemostatic drug desmopressin, may improve the impairment of primary haemostasis due to mildly decreased temperature.

02

Conditions studied

  • Hypothermia Induced Impairment of Primary Haemostasis

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03

In context

Hypothermia

499 studies on the registry are indexed under Hypothermia; 54 are open to participants now.

This study's planned enrollment of 48 is below the median of 80 across 351 interventional studies indexed under Hypothermia.

Browse Hypothermia studies →

Lead sponsor

The University of Hong Kong is the lead sponsor of 1,262 studies on the registry; 340 are open to participants now.

Of its 8 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  1. Healthy volunteers

Exclusion criteria

Exclusion Criteria:

  1. Any known platelet or coagulation disorder.
  2. Pregnant or lactating women.
  3. Known chronic liver or renal disease.
  4. Coronary artery, carotid artery or peripheral artery disease
  5. Recent history of taking antiplatelet drugs, anticoagulants or herbal preparations.
  6. Smoker or alcohol user
  7. Mentally incapable of providing informed consent
  8. Students or junior staff members who had direct working relationship with the PI
05

Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
48 participants (estimated)

Study arms

  • Active comparator
    desmopressin 1.5

    Drug: desmopressin

  • Active comparator
    desmopressin 3

    Drug: desmopressin

  • Active comparator
    desmopressin 15

    Drug: desmopressin

  • Placebo comparator
    placebo

    Drug: placebo

Interventions

  • Drugdesmopressin

    single desmopressin subcutaneous injection, 1.5mcg

  • Drugdesmopressin

    single desmopressin subcutaneous injection, 3mcg

  • Drugdesmopressin

    single desmopressin subcutaneous injection, 15mcg

  • Drugplacebo

    saline subcutaneous

06

What researchers measure

Primary outcomes

  1. closure time on PFA-100

    Time frame: 3 hours

07

Study locations

1 site
  • The University of Hong Kong
    Hong Kong, Hong Kong HKSAR, China
    • Kwok F.J. Ng, MBChB, MD, FANZCA, FHKAM, MBA · Contact · jkfng@hku.hk · (852) 28553303
    • Kwok F. J. Ng, MD,MBA · Principal investigator
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 14, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00902057
Lead sponsor
The University of Hong Kong
First posted
May 14, 2009
Start date
Jun 2009
Primary completion
Dec 2010 (estimated)
Completion
Jun 2011 (estimated)
Last update
May 14, 2009

Study contacts

Kwok F.J. Ng, MBChB, MD, MBA, FANZCA, FHKAM
Contact
jkfng@hku.hk
(852) 28553303
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2009. You cannot join it, but the record below documents what was studied.

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