An observational study in Kidney Scarring Post-Febrile UTI, sponsored by Hillel Yaffe Medical Center. Status unknown at 1 site in Israel. Open to participants aged Up to 7 Years. Per ClinicalTrials.gov, last updated 2009-03-24.
Sponsored by Hillel Yaffe Medical Center · Observational
The prevalence of kidney scarring after UTI is approximately 5-57%. UTIs are caused mainly by bacteria that cause local and systemic immunological reaction that are accompanied by cytokines. These cytokines are a main factor in the inflammatory process. They are produced by leukocytes, macrophages, fibroblasts, endothelial cells and epithelial cells in the kidney tissue. Interleukin 6 and 8 (IL-6 IL-8) were found in high levels in the urine of children and adults who suffer from UTIs. Other studies on animals have found a relationship between inflammatory reaction and scarring in the kidney. We hypothesize that we will find a similar relationship between the level of IL-6, IL-8 in the urine during acute pyelonephritis in children and the probability of kidney scarring.
149 studies on the registry are indexed under Glomerulonephritis; 38 are open to participants now.
This study's planned enrollment of 35 is below the median of 100 across 34 observational studies indexed under Glomerulonephritis.
Browse Glomerulonephritis studies →Hillel Yaffe Medical Center is the lead sponsor of 301 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Hospitalized children with UTIs
Exclusion Criteria:
High prevalence of kidney scarring in children with high levels of urine interleukins
Time frame: six months
This study is status unknown, as verified in Mar 2009. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Hillel Yaffe Medical Center