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CompletedNCT00809107FRETUpdated Feb 19, 2009

Frozen Embryo Transfer (FET) in Natural Cycles or in Natural Cycles Controlled by Human Chorionic Gonadotropin (hCG) Administration

An interventional study of HCG in Infertility, sponsored by Universitair Ziekenhuis Brussel. Completed at 1 site in Belgium. Open to female participants aged 17 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2009-02-19.

Sponsored by Universitair Ziekenhuis Brussel · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
150
Allocation
Randomized
Ages
17 Years to 40 Years
Sex
Female
01

Study summary

The rational of the study is to assess the implantation, pregnancy and live birth rates after the transfer of frozen- thawed embryos in natural cycles with spontaneous Luteinizing Hormone (LH)/Progesterone rise or in natural cycles controlled by human chorionic gonadotropin (hCG) for final oocyte maturation and ovulation.

02

Conditions studied

  • Infertility

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Keywords

  • natural cycle
  • FET
  • spontaneous LH pic
  • HCG
03

In context

Infertility

2,540 studies on the registry are indexed under Infertility; 405 are open to participants now.

This study's planned enrollment of 150 is above the median of 120 across 1,722 interventional studies indexed under Infertility.

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Lead sponsor

Universitair Ziekenhuis Brussel is the lead sponsor of 374 studies on the registry; 106 are open to participants now.

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Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
17 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • age \<40
  • BMI:18-29Kg/m2
  • day 3 embryo transfers
  • previously IVF or ICSI

Exclusion criteria

Exclusion Criteria:

  • irregular cycles
  • oocyte donation cycles
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
150 participants (estimated)

Study arms

  • Experimental
    1

    HCG GROUP

    Drug: HCG

  • No intervention
    2

    LH pick

Interventions

  • DrugHCG

    5000IU

    Also known as: pregnyl

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What researchers measure

Primary outcomes

  1. Implantation rate

    Time frame: 2 years

Secondary outcomes

  1. Ongoing pregnancy rate

    Time frame: 2 years

07

Study locations

1 site
  • Centre of Reproductive Medicine
    Brussels, 1090, Belgium
08

References and documents

Publications

  • Gelbaya TA, Nardo LG, Hunter HR, Fitzgerald CT, Horne G, Pease EE, Brison DR, Lieberman BA. Cryopreserved-thawed embryo transfer in natural or down-regulated hormonally controlled cycles: a retrospective study. Fertil Steril. 2006 Mar;85(3):603-9. doi: 10.1016/j.fertnstert.2005.09.015. PubMed 16500326 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 19, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00809107
Lead sponsor
Universitair Ziekenhuis Brussel
First posted
Dec 17, 2008
Start date
Oct 2006
Primary completion
Jul 2008
Completion
Jan 2009
Last update
Feb 19, 2009

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Feb 2009. You cannot join it, but the record below documents what was studied.

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