An observational study in Anorexia Nervosa, sponsored by New York State Psychiatric Institute. Completed at 1 site in United States. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-10-26.
Sponsored by New York State Psychiatric Institute · Observational
This is a research study to determine whether a medication called D-cycloserine (DCS) in combination with a type of psychotherapy called Exposure Therapy is helpful to patients with anorexia nervosa.
This is a research study to determine whether a medication called D-cycloserine (DCS) in combination with a type of psychotherapy called Exposure Therapy is helpful to patients with anorexia nervosa. DCS is approved by the FDA as an antibiotic medication, but has not been approved by the FDA for the treatment of anorexia nervosa. Past studies have found that DCS together with Exposure Therapy can help people with height phobia, social phobia, and obsessive compulsive disorder. Anorexia nervosa often includes phobia-like fears, obsessive thoughts, and compulsive rituals, so the current study aims to determine whether DCS paired with Exposure Therapy can also help people with anorexia nervosa. Anorexia nervosa is a disorder characterized by self-starvation, extreme weight loss, and difficulty maintaining a normal weight. You have been asked to participate in this study because you have been given a diagnosis of anorexia nervosa. In this study you will receive one of three therapies: Exposure Therapy with DCS, Exposure Therapy with placebo (inactive medication), or Treatment as Usual. You will participate in a total of four test meals in a laboratory setting. A total of 70 individuals with anorexia nervosa will participate in this study. Twenty individuals who have never had an eating disorder will participate in one portion of this study.
411 studies on the registry are indexed under Anorexia; 67 are open to participants now.
This study's enrollment of 32 is below the median of 65 across 104 observational studies indexed under Anorexia.
Browse Anorexia studies →New York State Psychiatric Institute is the lead sponsor of 425 studies on the registry; 26 are open to participants now.
Of its 50 completed or terminated interventional studies of FDA-regulated products, 45 (90%) have results posted.
Counted across the registry records on this site, refreshed daily.
Inpatients receiving treatment for anorexia nervosa
Inclusion Criteria for Patients:
Exclusion Criteria for Patients:
Inclusion Criteria for Healthy Controls:
Exclusion Criteria for Healthy Controls:
Exposure Therapy + D-Cycloserine
Behavioral: Exposure Therapy + D-Cycloserine
Exposure Therapy + Placebo
Behavioral: Exposure Therapy + Placebo
Supportive psychotherapy
Behavioral: Supportive Psychotherapy
Exposure therapy with d-cycloserine medication
Exposure therapy with placebo medication
Supportive psychotherapy
This study is completed, as verified in Oct 2012. You cannot join it, but the record below documents what was studied.
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New York State Psychiatric Institute