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Status unknownNCT00742378Updated Sep 23, 2008

Discriminating Ability of the Cirrus High Definition (HD) Optical Coherence Tomography (OCT) for Glaucoma

An observational study in Glaucoma, sponsored by Yonsei University. Status unknown at 1 site in Korea, Republic of. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2008-09-23.

Sponsored by Yonsei University · Observational

The sponsor has not verified this record recently (last verified Sep 2008), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
200
Ages
18 Years to 70 Years
Sex
All
01

Study summary

The Cirrus HD OCT, a new spectral domain optical coherence tomography, has better resolution than the previous OCT. Reproducibility and discriminating ability of the Cirrus HD OCT for glaucoma detection will be studied.

Read the detailed description

The Cirrus HD OCT is a newly developed imaging device of the spectral domain optical coherence tomography. Even though its resolution and speed are much better than the previous OCT, its reproducibility and diagnostic power for detecting the glaucomatous defect of retinal nerve fiber layer (RNFL) have not known yet. In the present study, we will review the data of RNFL thickness measurement using the Cirrus HD OCT. After assessing the inter-test variability, the discriminating ability of the Cirrus HD OCT for glaucoma diagnosis will be determined by the ROC curves.

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Conditions studied

  • Glaucoma

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Keywords

  • Glaucoma
  • Retinal nerve fiber layer
  • Cirrus OCT
03

In context

Glaucoma

1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.

This study's planned enrollment of 200 is above the median of 103 across 454 observational studies indexed under Glaucoma.

Browse Glaucoma studies →

Lead sponsor

Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Glaucoma patients and normal controls

Inclusion criteria

  • Cooperative patients
  • Repeated OCT data

Exclusion criteria

Exclusion Criteria:

  • Intraocular surgeries history
  • DM
  • High refractive error ( \< -4.00 diopters, or > + 4.00 diopters)
  • Media opacity
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Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
200 participants (estimated)

Groups and cohorts

  • C

    Normal controls

  • G

    Glaucoma

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What researchers measure

Primary outcomes

  1. Retinal nerve fiber layer thickness

    Time frame: when the OCT images are taking

Secondary outcomes

  1. Red-free fundus photo

    Time frame: when the OCT images are taking

  2. Visual field

    Time frame: when the OCT images are taking

  3. Intraocular pressure

    Time frame: when the OCT images are taking

07

Study locations

1 of 1 sites recruiting
  • Gong Je Seong
    Seoul, 135-720, Korea, Republic of
    • Gong Je Seong, MD, PhD · Contact · gjseong@yuhs.ac · 82-2-2019-3441
    • Gong Je Seong, MD, PhD · Principal investigator
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 23, 2008, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00742378
Lead sponsor
Yonsei University
First posted
Aug 27, 2008
Start date
Sep 2008
Primary completion
Oct 2008 (estimated)
Completion
Dec 2008 (estimated)
Last update
Sep 23, 2008

Study contacts

Gong Je Seong, MD, PhD
Contact
gjseong@yuhs.ac
82-2-2019-3441
Gong Je Seong, MD, PhD
principal investigator · Yonsei University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2008. You cannot join it, but the record below documents what was studied.

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