An interventional study of Virtual Reality Exposure Therapy for agoraphobic participants and Standard exposure in vivo for agoraphobic participants in Panic Disorder and Agoraphobia, sponsored by VU University of Amsterdam. Completed at 1 site in Netherlands. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2018-09-13.
Sponsored by VU University of Amsterdam · Not applicable, Interventional, and Treatment
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Virtual Reality Exposure Therapy (VRET) is an effective treatment for anxiety disorders, particularly for specific phobias as fear of heights and fear of flying (e.g. Powers \& Emmelkamp, 2008). Recent technological advances (e.g. more realistic avatars) make research into the efficacy of VRET for participants with elevated agoraphobic symptoms desirable. Therefore, the aim of the present research proposal is to investigate the comparative efficacy of:
270 studies on the registry are indexed under Panic Disorder; 37 are open to participants now.
This study's enrollment of 55 is below the median of 77 across 215 interventional studies indexed under Panic Disorder.
Browse Panic Disorder studies →VU University of Amsterdam is the lead sponsor of 48 studies on the registry; 8 are open to participants now.
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Exclusion Criteria:
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The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
DSM diagnostic criteria
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Virtual Reality Exposure Therapy for agoraphobic participants
Behavioral: Virtual Reality Exposure Therapy for agoraphobic participants
Standard exposure in vivo for panic disorder
Behavioral: Standard exposure in vivo for agoraphobic participants
Wait-list control group. Participants from this arm are randomized to the two active conditions after 10 weeks of waiting.
This intervention is comprised of 10 sessions of cognitive behavior therapy for panic disorder and agoraphobia with components of * Psycho-education, breathing training and cognitive restructuring * Virtual reality Exposure to agoraphobic situations and interoceptive exposure * Relapse prevention
This intervention is comprised of 10 sessions of cognitive behavior therapy for panic disorder and agoraphobia with components of * Psycho-education, breathing training and cognitive restructuring * Standard exposure in vivo to agoraphobic situations and interoceptive exposure * Relapse prevention (according to the protocol of Craske \& Barlow)
Panic Disorder Severity Scale (PDSS); Mobility Inventory for Agoraphobia (MI); Behavioural Avoidance Test (BAT)
Time frame: Assessed at pre- and post-treatment and 6-12 months follow-up
Beck Anxiety Inventory (BAI); Anxiety Sensitivity Inventory (ASI); Beck Depression Inventory (BDI); Panic Disorder Severity Scale (PDSS); Agoraphobic Cognitions Questionnaire (ACQ); Bodily Sensations Questionnaire (BSQ); Panic Appraisal Inventory (PAI)
Process measures are taken prior to treatment, after the fourth treatment session and at post-treatment. The same measures will also be taken at 6 months follow-up.
Time frame: Process measures: are taken prior to treatment, after the fourth treatment session and at post-treatment. The PDSS and PAI will be administered every therapy session
The record gives a start of Oct 2008, a primary completion of Jun 2011 and a completion of Jan 2012. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Sep 2018. You cannot join it, but the record below documents what was studied.
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VU University of Amsterdam