An interventional study of Ct-guided pleural needle biopsy and Thoracoscopy in Pleural Effusion and Pleural Diseases, sponsored by Eskisehir Osmangazi University. Completed at 1 site in Turkey. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2008-07-23.
Sponsored by Eskisehir Osmangazi University · Not applicable, Interventional, and Diagnostic
The aim of this study is to compare the rigid thoracoscopy with CT-guided pleural needle biopsy by the diagnostic efficacy and safety in patients with pleural effusion.
Pleural needle biopsy with Abrams needle, which can be performed by all chest physicians, is a simple, safe and cheap method of obtaining tissue from pleura, but its diagnostic rate is between 7 % -72 %, \~ 50 %. Problems for Abrams needle are scattered tumoral involvement on pleura, blind performance, small tissue sampling, to tend to early and dense fibrosis and usually involvement of lower pleural surface and diaphragmatic pleura.
Pleural needle biopsy with Abrams' needle, which can be performed by all chest physicians, if done with image guided and if this increase the diagnosis rate, the number of second procedure which is more expensive and hard will decrease.
The study aims the comparison of rigid thoracoscopy with CT-guided pleural needle biopsy by the diagnostic efficacy and safety in patients with pleural effusion.
It has been planned that a total of 120 patients accepted to the study who have pleural effusion at plain chest roentgenogram. All patients are being randomized after underwent contrast-enhanced CT. Undiagnosed patients of biopsy group are performed thoracoscopy and undiagnosed patients of thoracoscopy group followed up.
Two groups will compare by age, sex, Karnofsky performance status (KPS), diagnosis and complication rate.
324 studies on the registry are indexed under Pleural Effusion; 62 are open to participants now.
This study's enrollment of 124 is above the median of 63 across 212 interventional studies indexed under Pleural Effusion.
Browse Pleural Effusion studies →Eskisehir Osmangazi University is the lead sponsor of 149 studies on the registry; 27 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
CT guided pleural needle biopsy
Procedure: Ct-guided pleural needle biopsy
Thoracoscopy
Procedure: Thoracoscopy
Biopsy of pleura
Also known as: Diagnose
Biopsy of pleura
Also known as: Diagnose
Efficacy and safety of both thoracoscopy and CT-guided pleural needle biopsy for diagnosis of pleural diseases
Time frame: 30 months
Determine the efficacy of pleural needle biopsy and thoracoscopy in relation to CT findings.
Time frame: 30 months
This study is completed, as verified in Jul 2008. You cannot join it, but the record below documents what was studied.
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Eskisehir Osmangazi University