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CompletedNCT00705094Updated Oct 1, 2014

Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients

An observational study in Testicular Cancer, Seminoma and Non-seminomatous, sponsored by AHS Cancer Control Alberta. Completed at 1 site in Canada. Open to male participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2014-10-01.

Sponsored by AHS Cancer Control Alberta · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
30
Ages
18 Years and older
Sex
Male
01

Study summary

For many years, researchers and doctors have studied different kinds of treatments to improve the survival of men with testicular cancer. However, recent research has shown that many years later, men who had testicular cancer appear to be at higher risk for developing heart disease (heart attack or heart failure), especially if they received chemotherapy. Since these studies were done many years after men received treatment, there was no way to know if other factors contributed to the health problems they experienced. This study is being done because it would be helpful to study heart function and cardiovascular disease risk factors of men who have been diagnosed with testicular cancer, before and after they receive chemotherapy treatment compared to men who receive treatment with surgery alone.

Read the detailed description

The aim of this pilot study is to examine global and regional LV systolic and diastolic function, cardiac output, cardiac reserve, VO2peak and CVD risk profile in males recently diagnosed with testicular cancer treated with surgery alone or surgery and chemotherapy.

02

Conditions studied

  • Testicular Cancer
  • Seminoma
  • Non-seminomatous

Keywords

  • cardiovascular risk factors
  • cardiac function
  • VO2peak
  • Chemotherapy
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In context

Testicular Neoplasms

295 studies on the registry are indexed under Testicular Neoplasms; 51 are open to participants now.

This study's planned enrollment of 30 is below the median of 133 across 73 observational studies indexed under Testicular Neoplasms.

Browse Testicular Neoplasms studies →

Lead sponsor

AHS Cancer Control Alberta is the lead sponsor of 187 studies on the registry; 24 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
Male
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

testicular cancer patients who have recieved surgery and are scheduled for either chemotherapy or surveillance

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • surgery and surveillance
  • surgery and multi-cycle chemotherapy
  • both good and intermediate prognosis seminoma and non-seminomatous germ cell testicular tumors
  • performance index > 70%
  • no to cardiopulmonary testing

Exclusion criteria

Exclusion Criteria:

  • documented cardiovascular disease or evidence of myocardial ischemia on the incremental exercise (VO2peak) test.
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Karnofsky performance status (KPS)

A 0–100 scale of how well someone can carry out everyday activities. 100 is no complaints and no signs of illness; 70 is able to look after yourself but not to work or keep up normal activity; 50 is needing considerable help and frequent medical care.

Studies often ask for 60 or 70 and above. Your doctor gives the score.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
30 participants (estimated)

Groups and cohorts

  • 1

    Testicular cancer patients who have received surgery and are scheduled for surveillance

  • 2

    Testicular cancer patients who have received surgery and are scheduled for chemotherapy

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Study locations

1 site
  • Cross Cancer Institute
    Edmonton, Alberta T6G 1Z2, Canada
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 1, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00705094
Responsible party
Sponsor
First posted
Jun 25, 2008
Start date
Sep 2008
Primary completion
May 2011
Completion
Jul 2012
Last update
Oct 1, 2014

Study contacts

Mark Haykowsky, PhD
principal investigator · University of Alberta

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2014. You cannot join it, but the record below documents what was studied.

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