An interventional study of Preimplantation genetic screening after embryo biopsy in In Vitro Fertilization, sponsored by KU Leuven. Completed at 1 site in Belgium. Open to participants aged 35 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2008-01-15.
Sponsored by KU Leuven · Not applicable, Interventional, and Basic science
In view of insufficient evidence to routinely use Preimplantation Genetic Screening (PGS) to improve success rates after IVF, we test the hypothesis that patients with advanced maternal age (AMA) have a higher implantation rate (IR) after embryo transfer (ET) of chromosomally normal embryos following PGS compared to patients who had an ET without PGS.
In a randomized controlled trial (RCT) in patients with AMA (≥ 35 years), the clinical IR per embryo transferred will be compared after ET on day 5 or 6 between the PGS group (embryo biopsy and analysis of chromosomes 13, 16, 18, 21, 22, X and Y) and the control group without PGS.
87 studies on the registry are indexed under Aneuploidy; 12 are open to participants now.
This study's enrollment of 100 is below the median of 152 across 36 interventional studies indexed under Aneuploidy.
Browse Aneuploidy studies →KU Leuven is the lead sponsor of 358 studies on the registry; 62 are open to participants now.
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Exclusion Criteria:
Procedure: Preimplantation genetic screening after embryo biopsy
Preimplantation genetic screening after embryo biopsy
Clinical implantation rate per embryo transferred
Time frame: end of study
Pregnancy rate per transfer
Time frame: end of study
This study is completed, as verified in Jan 2008. You cannot join it, but the record below documents what was studied.
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KU Leuven