An observational study in Infertility, Female, Infertility, Male and Infertility, sponsored by Gattaca Genomics. Enrolling by invitation at 1 site in United States. Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-01-29.
Sponsored by Gattaca Genomics · Observational
The goal of this observational study is to discern if there is a relationship between timelapse imagery of human oocytes/embryos and PGT results.
Embryos of patients that are undergoing PGT will be placed into a timelapse incubator. The data obtained by the timelapse incubator will be used in conjunction with the PGT data to determine any relationships.
Timelapse imagery (TLI) is a multifaceted technology being utilized within the in vitro fertilization (IVF) space. With this technology it is possible to have a live, continuous video of embryo development from fertilization to implantation. During this live evaluation multiple datapoints can be extrapolated and used to determine embryo viability. Another technology used in the IVF space is preimplantation genetic testing for aneuploidy (PGT-A). With this technology, individual cells from the embryo are removed, amplified, and the chromosomal content of the cells is analyzed by next generation sequencing (NGS)-based technology, allowing the chromosomal content of the embryos to be determined prior to embryo transfer.
To date, no one has combined the data from both tools to try to advance the IVF field.
Gattaca Genomics is proposing utilizing the data obtained from TLI, in conjunction with the data obtained from PGT-A, to create a computer model that can accurately predict which embryos will lead to a successful outcome during IVF.
552 studies on the registry are indexed under Infertility, Female; 137 are open to participants now.
This study's planned enrollment of 2,000 is above the median of 161 across 162 observational studies indexed under Infertility, Female.
Browse Infertility, Female studies →This is the only study on the registry with Gattaca Genomics as lead sponsor.
Counted across the registry records on this site, refreshed daily.
All infertile patients undergoing IVF with PGT
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Infertile patients undergoing IVF with PGT.
Diagnostic Test: Timelapse incubation and PGT
Patients will have their embryos cultured in a timelapse incubator and their PGT results will be compared to the data collected during timelapse incubation.
Time to first cleavage
time of embryo to undergo first cleavage
Time frame: 24 hours
Time to blastulation
time of embryo to form a blastocoel
Time frame: 5-7 days
Fertilization morphology
the morphological appearance of the pronuclei
Time frame: 24 hours
Embryo morphology
the morphological appearance of the embryos
Time frame: 2-7 days
Patient age
Patient age
Time frame: 0 days
Partner age
Partner age
Time frame: 0 days
Partner diagnosis
Partner diagnosis
Time frame: 0 days
Metabolomics of culture media
measurement of the spent culture media for amino acids, enzymes, and metabolites
Time frame: 7 days
AMH
antimullerian hormone level in female's blood
Time frame: 0 days
Days of stimulation
the number of days the patient underwent stimulation for IVF
Time frame: 0-15 days
Dosage of stimulation meds
the amount of stimulation meds the patient took during IVF treatment
Time frame: 0-15 days
Pregnancy
initial bhCG levels
Time frame: 2 weeks after transfer
Patient diagnosis
Number of patients with each specific diagnosis, including low ovarian reserve, PCOS, primary infertility, secondary infertility, endometrosis, and unknown infertility.
Time frame: 0 days
implantation
Number of patients that develope a sac within the uterus post transfer
Time frame: 4 weeks post transfer
fetal cardiac heartbeat
Number of patients that develop a fetal cardiac heartbeat after transfer
Time frame: 6 weeks
livebirth
Number of patients that have a livebirth of an infant after IVF
Time frame: approximately 9 months after transfer
Plan to share: No — Data will not be shared with other researchers
No publications or documents are linked to this record.
Started Jan 2025 (actual). Primary completion is estimated for Jun 2031, 77 months after the start.
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No contact was published for this record. The registry link below has the sponsor’s details.
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