An observational study in Vertigo, sponsored by Boston University. Completed. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-06-23.
Sponsored by Boston University · Observational
The purpose of this study is to determine the potential usefulness of new functional MRI in diagnostic assessment of patients presenting with vertigo.
The incidence of vertigo has been reported to be as high as 1.5% in the general population and some reports suggest that more than 5% of adults experience some kind of vertigo each year. In 80% of affected individuals, this symptom resulted in a medical consultation, interruption of daily activities, or sick leave. Therefore, vertigo can have a significant impact on health and well being. Unfortunately, there is not yet any satisfactory objective method for diagnosis of vertigo. At present, the diagnosis usually depends on medical history, vestibular function tests, Dix-Hallpike positioning tests done in the office, and, to some extent imaging studies doen to look for such abnormalities such as acoustic tumor, brain tumor, and evidence of multiple sclerosis. A number of recent studies support the possibility of using functional MRI (fMRI), particularly a new diffusion tensor fiber tracking (DTT) technique, as a new tool for diagnosis of disorders that can cause vertigo. In this study, our hypothesis is that there is an alteration in the activity in neural pathways of patients with vertigo that can be detected by fMRI. To test this assumption, our objective in this study is to determine whether there is a difference between the fMRI images obtained in normal subjects versus those in patients with vertigo.
248 studies on the registry are indexed under Vertigo; 39 are open to participants now.
This study's enrollment of 4 is below the median of 151 across 50 observational studies indexed under Vertigo.
Browse Vertigo studies →Boston University is the lead sponsor of 266 studies on the registry; 37 are open to participants now.
Of its 30 completed or terminated interventional studies of FDA-regulated products, 24 (80%) have results posted.
Counted across the registry records on this site, refreshed daily.
primary care clinic
Exclusion Criteria:
Healthy volunteers devoid of any ear problems
Device: Functional MRI imaging
Patients with the symptoms of vertigo
Device: Functional MRI imaging
The functional MRI imaging of whole brain will be obtained before, during and after the vestibular response which is induced by the designated caloric stimulation. Post-imaging analysis will reveal which region or neural pathways in the central nervous system may attributed to the development of vertigo.
Also known as: Magnetic Resonance Imaging
Activation of target sites on the functional MRI images during the vestibular response
Time frame: Not specific
Differences in the fiber tracking of central nervous system specifically involved in the vestibular response
Time frame: Not specific
No study locations are listed for this record.
This study is completed, as verified in Jun 2011. You cannot join it, but the record below documents what was studied.
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Boston University