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CompletedNCT00583934Updated Jul 13, 2010

Is Screening for Esophageal Pathology in Asymptomatic Patients Post-Treatment for Head and Neck Cancer Beneficial?

An observational study in Esophageal Cancer, sponsored by University of California, Davis. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-07-13.

Sponsored by University of California, Davis · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
19
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to evaluate the prevalence of esophageal pathology in asymptomatic patients with a history of head and neck cancer.

Read the detailed description

There are certain factors (i.e. alcohol, tobacco, decreased saliva production from radiation) that predispose patients with a history of head and neck cancer to have esophageal disease. Often, in the initial stages of the disease, patients do not have symptoms. However, the early detection of precancerous lesions or small cancers improves patients' chances of being cured. There is no direct data supporting the practice of screening patients with a history of head and neck cancer after treatment for esophageal disease if they are not experiencing symptoms. However, many argue that screening endoscopy is justified in high risk patients to detect early esophageal cancer or dysplasia at a curable state. We are, therefore, performing this study to determine the value of endoscopic screening of the esophagus after treatment for head and neck cancer in patients without symptoms.

02

Conditions studied

  • Esophageal Cancer

Keywords

  • esophageal cancer, head and neck cancer, dysplasia
03

In context

Head and Neck Neoplasms

2,344 studies on the registry are indexed under Head and Neck Neoplasms; 551 are open to participants now.

This study's enrollment of 19 is below the median of 100 across 441 observational studies indexed under Head and Neck Neoplasms.

Browse Head and Neck Neoplasms studies →

Lead sponsor

University of California, Davis is the lead sponsor of 798 studies on the registry; 146 are open to participants now.

Of its 65 completed or terminated interventional studies of FDA-regulated products, 43 (66%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Subject population will be recruited from the clinical practice of the investigators.

Inclusion criteria

  • Head and neck cancer patients that are six months post treatment and asymptomatic for esophageal disease.

Exclusion criteria

Exclusion Criteria:

  • None if meets the inclusion criteria.
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
19 participants (actual)
Biospecimen retention
Samples with dna

Groups and cohorts

  • A

    Those six months post treatment for head and neck cancer.

06

What researchers measure

Primary outcomes

  1. Early detection of esophageal cancer or dysplasia in patients without symptoms, after treating their primary cancer, may improve their chances of being cured of a secondary disease.

07

Study locations

1 site
  • University of California Davis Medical Center
    Sacramento, California 95817, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 13, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00583934
Lead sponsor
University of California, Davis
First posted
Jan 2, 2008
Start date
Sep 2007
Primary completion
Nov 2009
Completion
Nov 2009
Last update
Jul 13, 2010

Study contacts

Gregory Farwell, MD
principal investigator · University of California, Davis

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2010. You cannot join it, but the record below documents what was studied.

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