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WithdrawnNCT00556686Updated Apr 22, 2015

Salivary Catecholamines in Aphthous Stomatitis (Canker Sores)

An observational study in Canker Sore, sponsored by University of California, Davis. Withdrawn. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-04-22.

Sponsored by University of California, Davis · Observational

Why this study was withdrawn
We are currently modifying the study
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
0
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to examine how compounds produced in patients with canker sores affect wound healing.

Read the detailed description

The purpose of this study is to determine if salivary catecholamines are elevated in patients with the disease aphthous stomatitis. The results of this study will be combined with those performed in collaboration with a co-Investigator to understand the effects of catecholamines on mucosal wound healing and oral epithelial cell migration.

02

Conditions studied

  • Canker Sore

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03

In context

Stomatitis, Aphthous

63 studies on the registry are indexed under Stomatitis, Aphthous; 17 are open to participants now.

Browse Stomatitis, Aphthous studies →

Lead sponsor

University of California, Davis is the lead sponsor of 809 studies on the registry; 142 are open to participants now.

Of its 67 completed or terminated interventional studies of FDA-regulated products, 43 (64%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

All subjects will be sampled from the community.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age 18 or older, both genders
  • History of recurrent aphthous ulcers with 4 or more episodes per year

Exclusion criteria

Exclusion Criteria:

  • History of salivary gland disease including Sjogren's disease, parotitis, and sialolithiasis
  • History of benign or malignant salivary gland tumor
  • History of celiac disease, ulcerative colitis or Crohn's disease
  • Patients on medications that affect salivary flow such as anti-depressants and anti-cholinergic medications
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
0 participants (actual)
Biospecimen retention
Samples without dna

Groups and cohorts

  • 1

    Individuals with a history of canker sores.

  • 2

    Individuals with no history of canker sores.

06

Study locations

No study locations are listed for this record.

07

References and documents

08

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Aug 2006, a primary completion of Dec 2009 and a completion of Dec 2009. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 8, 2007
First posted
Nov 12, 2007
Start
Aug 2006
Primary completionEst.
Dec 2009
CompletionEst.
Dec 2009
Last update
Apr 22, 2015
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 22, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00556686
Responsible party
Sponsor
First posted
Nov 12, 2007
Start date
Aug 2006
Primary completion
Dec 2009 (estimated)
Completion
Dec 2009 (estimated)
Last update
Apr 22, 2015

Study contacts

Nasim Fazel, MD, DDS
principal investigator · University of California, Davis

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Apr 2015. You cannot join it, but the record below documents what was studied.

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Discussion

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