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Status unknownNCT00533754Updated Sep 21, 2007

Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population

An interventional study of drawing blood in Age-Related Macular Degeneration, sponsored by Rudolf Foundation Clinic. Status unknown at 1 site in Austria. Open to participants aged 55 Years and older. Per ClinicalTrials.gov, last updated 2007-09-21.

Sponsored by Rudolf Foundation Clinic · Not applicable, Interventional, and Basic science

The sponsor has not verified this record recently (last verified Sep 2007), so the status shown — last known as Active, not recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Allocation
Not applicable
Ages
55 Years and older
Sex
All
01

Study summary

The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals.

Additionaly a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD.

02

Conditions studied

  • Age-Related Macular Degeneration

Keywords

  • age-related macular degeneration, genetics
03

In context

Macular Degeneration

1,474 studies on the registry are indexed under Macular Degeneration; 206 are open to participants now.

Browse Macular Degeneration studies →

Lead sponsor

Rudolf Foundation Clinic is the lead sponsor of 5 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
55 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • man and women over 18 years old
  • Filled out informed consentBereitschaft zur Teilnahme
  • Diagnosis of non-exudative/ exudative age related macular dgeneneration

Exclusion criteria

Exclusion Criteria:

  • inherited retinal diseases
  • other aquired retinal/ macular
  • missing informed consent
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
Single (Outcomes assessor)

Interventions

  • Proceduredrawing blood
06

What researchers measure

Primary outcomes

  1. higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals

Secondary outcomes

  1. a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD

07

Study locations

1 site
  • Rudoulf foundation Clinic
    Vienna, 1030, Austria
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 21, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00533754
Lead sponsor
Rudolf Foundation Clinic
First posted
Sep 21, 2007
Start date
Jul 2006
Completion
Nov 2007 (estimated)
Last update
Sep 21, 2007

Study contacts

Susanne Binder, M.D.
study chair · Rudoulf Foundation Clinic

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2007. You cannot join it, but the record below documents what was studied.

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