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CompletedNCT00533403Updated Jun 26, 2015

MK0686 in Postsurgery Dental Pain (0686-002)

A Phase 2 interventional study of MK0686 in Pain, Postoperative, sponsored by Merck Sharp & Dohme LLC. Completed. Open to participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2015-06-26.

Sponsored by Merck Sharp & Dohme LLC · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Enrollment
114
Allocation
Randomized
Ages
18 Years to 45 Years
Sex
All
01

Study summary

To compare the pain relieving effect of MK0686 to placebo or ibuprofen after dental surgery.

02

Conditions studied

  • Pain, Postoperative

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03

In context

Pain, Postoperative

5,089 studies on the registry are indexed under Pain, Postoperative; 1,137 are open to participants now.

This study's enrollment of 114 is above the median of 75 across 4,341 interventional studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

Merck Sharp & Dohme LLC is the lead sponsor of 2,111 studies on the registry; 130 are open to participants now.

Of its 488 completed or terminated interventional studies of FDA-regulated products, 361 (74%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 45 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Men and women ages 18-45 years who are scheduled to have 2 or more third molars (wisdom teeth) removed
  • Patients must agree to remain in the clinic for 24 hours after surgery

Exclusion criteria

Exclusion Criteria:

  • Patient has history of heart disease, asthma, pulmonary disease
  • Patient must discontinue use of certain pain medicines 24-72 hours prior to the surgery
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
114 participants (actual)

Interventions

  • DrugMK0686
06

Study locations

No study locations are listed for this record.

07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 26, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00533403
Lead sponsor
Merck Sharp & Dohme LLC
Responsible party
Sponsor
First posted
Sep 21, 2007
Start date
Jul 2004
Primary completion
Nov 2004
Completion
Nov 2004
Last update
Jun 26, 2015

Study contacts

Medical Monitor
study director · Merck Sharp & Dohme LLC
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2015. You cannot join it, but the record below documents what was studied.

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