An interventional study of altitude exposure in Obstructive Sleep Apnea Syndrome, sponsored by University of Zurich. Completed at 1 site in Switzerland. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2010-05-26.
Sponsored by University of Zurich · Not applicable and Interventional
The purpose of the study is to investigate the effect of an altitude sojourn on patients with the obstructive sleep apnea syndrome
Previous observations do not allow to draw firm conclusions on the effect of altitude sojourn on sleep, breathing and daytime performance in patients with the obstructive sleep apnea syndrome. Furthermore, the susceptibility of sleep apnea patients to high altitude related illness is not known. Therefore, the purpose is to study untreated patients with obstructive sleep apnea syndrome living at low altitude during a sojourn of a few days at moderate altitude in order to evaluate the physiologic effects of hypobaric hypoxia in these patients. We hypothesize that: 1. Sleep and nocturnal breathing disturbances in untreated OSA patients are more pronounced at moderate altitude compared to low altitude. 2. The increase in sleep related breathing disturbances at moderate altitude is due to an increase in central apnea/hypopnea
1,423 studies on the registry are indexed under Apnea; 160 are open to participants now.
This study's planned enrollment of 40 is below the median of 51 across 966 interventional studies indexed under Apnea.
Browse Apnea studies →University of Zurich is the lead sponsor of 1,030 studies on the registry; 130 are open to participants now.
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Exclusion Criteria:
sojourn at moderate altitude (1860m and 2590m) during 2 days/nights each
Prevalence and severity of sleep disordered breathing
Time frame: during altitude sojourn
alterations in sleep structure and vigilance; high altitude related illness
Time frame: during altitude sojourn
This study is completed, as verified in May 2010. You cannot join it, but the record below documents what was studied.
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University of Zurich