CClinicalTrials.gg
Status unknownNCT00501475Updated Jul 27, 2010

NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED

A Phase 4 interventional study of NAC Bicarbonate in Chronic Renal Failure, sponsored by Seoul National University Hospital. Status unknown at 2 sites in Korea, Republic of. Open to participants aged 15 Years and older. Per ClinicalTrials.gov, last updated 2010-07-27.

Sponsored by Seoul National University Hospital · Phase 4, Interventional, and Prevention

The sponsor has not verified this record recently (last verified Jul 2010), so the status shown — last known as Recruiting — may be out of date.
Phase
Phase 4
Study type
Interventional
Allocation
Randomized
Ages
15 Years and older
Sex
All
01

Study summary

The purpose of this study is to evaluate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography scan is checked in emergency room.

Read the detailed description

CIN is frequent in CRF patients. However most studies about CIN has been focusing on elective PCI patients. There is no study that the NAC nor sodium bicarbonate would help in preventing CIN in CRF patients who need enhanced CT scan in ED.

Our intention was to investigate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography scan is checked in emergency room.

02

Conditions studied

  • Chronic Renal Failure

Keywords

  • N-acetylcysteine
  • nephropathy
  • bicarbonate
03

In context

Kidney Failure, Chronic

2,085 studies on the registry are indexed under Kidney Failure, Chronic; 261 are open to participants now.

Browse Kidney Failure, Chronic studies →

Lead sponsor

Seoul National University Hospital is the lead sponsor of 1,859 studies on the registry; 274 are open to participants now.

Of its 12 completed or terminated interventional studies of FDA-regulated products, 2 (17%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years and older
Sexes eligible
All

Inclusion criteria

  • CRF patients who need enhanced CT scan

Exclusion criteria

Exclusion Criteria:

  • less than 15 years old
  • hypersensitivity to NAC
  • on dialysis
  • no consent from patient or next of kin
05

Study design

Phase
Phase 4
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)

Interventions

  • DrugNAC Bicarbonate
06

What researchers measure

Primary outcomes

  1. the rate of CIN

    Time frame: 3 days after CT scan

Secondary outcomes

  1. mortality

    Time frame: 30 days after CT scan

07

Study locations

2 of 2 sites recruiting
  • Seoul National University Hospital
    Seoul, 28 Yongon-dong, Chongro-gudo 110-744, Korea, Republic of
    Recruiting
  • Seoul National University Bundang Hospital
    Seongnam-si, Gyeongi-do 463-707, Korea, Republic of
    • Joong Eui Rhee, MD · Contact · rheeje@snubh.org · 82-31-787-3049
    • Kyuseok Kim, MD · Principal investigator
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 27, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00501475
Lead sponsor
Seoul National University Hospital
First posted
Jul 16, 2007
Start date
Mar 2007
Completion
Oct 2010 (estimated)
Last update
Jul 27, 2010

Study contacts

Kyuseok Kim, M.D
Contact
dremkks@snubh.org
82-31-787-3049
Kyuseok Kim, MD
principal investigator · Seoul National University Bundang Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jul 2010. You cannot join it, but the record below documents what was studied.

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