CClinicalTrials.gg
CompletedNCT00480337Updated Dec 17, 2008

In Vitro Maturation of Immature Oocytes

An interventional study of In Vitro Maturation of immature oocytes in Polycystic Ovary Syndrome and Ovarian Hyperstimulation Syndrome, sponsored by Sheba Medical Center. Completed at 1 site in Israel. Open to female participants aged 20 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2008-12-17.

Sponsored by Sheba Medical Center · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Allocation
Non-randomized
Ages
20 Years to 45 Years
Sex
Female
01

Study summary

The aim of this study is to aspirate immature oocytes from antral follicles and mature the oocytes in vitro. These mature oocytes will serve for fertilization and the creation of embryos which will be replace in the uterus as performed during normal IVF.We will record the efficacy and safety of this procedure.

02

Conditions studied

  • Polycystic Ovary Syndrome
  • Ovarian Hyperstimulation Syndrome

Keywords

  • PCOS
  • Fertility Preservation
  • Repeated IVF Failure
  • S/P Hyperstimulation
03

In context

Polycystic Ovary Syndrome

944 studies on the registry are indexed under Polycystic Ovary Syndrome; 174 are open to participants now.

Browse Polycystic Ovary Syndrome studies →

Lead sponsor

Sheba Medical Center is the lead sponsor of 660 studies on the registry; 63 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 45 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Women with PCOS
  • Women with previous Hyperstimulation or with risk of developing hyperstimulation during IVF Treatment
  • Women diagnosed with cancer who are interested in fertility preservation
  • Women with repeated IVF failure

Exclusion criteria

Exclusion Criteria:

  • Severe cases of endometriosis
  • Large myomas
  • Hydrosalpinxs Technical problem with previous oocytes pick-up
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)

Interventions

  • ProcedureIn Vitro Maturation of immature oocytes
06

Study locations

1 site
  • IVF Unit, Shea Medical Center, Tel-Hashomer
    Ramat-Gan, 52621, Israel
07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 17, 2008, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00480337
Lead sponsor
Sheba Medical Center
First posted
May 30, 2007
Last update
Dec 17, 2008

Study contacts

Ariel Hourvitz
principal investigator · IVF Unit, Sheba Medical Center

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2008. You cannot join it, but the record below documents what was studied.

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