A Phase 2/3 interventional study of Amniotic membrane transplantation using fibrin glue in Pterygium, sponsored by Chulalongkorn University. Completed at 1 site in Thailand. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2008-02-13.
Sponsored by Chulalongkorn University · Phase 2/3, Interventional, and Treatment
The purpose of this study is to compared between conventional pterygium excision and AMT transplantation with suture and with fibrin glue.
There are few studies about use of fibrin glue in pterygium surgery with conjunctival auto-graft with promising outcome. Less recurrent rate, less discomfort and halve surgical time were reported.
Up to our knowledge,there is no report of fibrin glue in pterygium excision with amniotic membrane transplantation(AMT). There is conventional technique to use AMT in King Chulalongkorn Memorial Hospital because some benefits over conjunctival auto-graft e.g.
111 studies on the registry are indexed under Pterygium; 10 are open to participants now.
This study's enrollment of 32 is below the median of 60 across 92 interventional studies indexed under Pterygium.
Browse Pterygium studies →Chulalongkorn University is the lead sponsor of 312 studies on the registry; 59 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®)
Procedure: Amniotic membrane transplantation using fibrin glue
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using continuous suture with nylon 10-0
Procedure: Amniotic membrane transplantation using fibrin glue
After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®) in 16 eyes of 16 patients of FG group and continuous suture with nylon 10-0 in 16 eyes of 16 patients of SU group.
Also known as: Quixil®, Nylon 10-0
Pain and discomfort during and after surgery using visual analog scale
Time frame: during surgery and after surgery up to 30 days
Surgical time
Time frame: start and to the end of surgery
Healing of epithelial defect on cornea and AMT
Time frame: until 30 days
Postoperative inflammation
Time frame: up to 30 days
Complications e.g. Recurrent, graft loss/dehiscent, re-operation
Time frame: until last follow up
This study is completed, as verified in Feb 2008. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Chulalongkorn University