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CompletedNCT00444119Updated Mar 7, 2007

Survey in Patients With Chronic Adrenal Insufficiency in Germany

An observational study in Adrenal Insufficiency and Addison's Disease, sponsored by University of Wuerzburg. Completed at 2 sites in Germany. Per ClinicalTrials.gov, last updated 2007-03-07.

Sponsored by University of Wuerzburg · Observational

Study type
Observational
Model
Defined population
Time perspective
Other
Sex
All
01

Study summary

The purpose of this survey is to assess patients with chronic primary or secondary adrenal failure regarding subjective health status, incidence and causes of adrenal crisis, hormone replacement regimens and concomitant endocrine or non endocrine disease.

02

Conditions studied

  • Adrenal Insufficiency
  • Addison's Disease

Keywords

  • adrenal insufficiency
  • subjective health status
  • quality of life
  • adrenal crisis
  • hormone replacement
  • DHEA
03

In context

Adrenal Insufficiency

132 studies on the registry are indexed under Adrenal Insufficiency; 26 are open to participants now.

Browse Adrenal Insufficiency studies →

Lead sponsor

University of Wuerzburg is the lead sponsor of 32 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • age > 18 years
  • chronic adrenal failure with disease duration > 12 months and hormone replacement therapy for cortisol deficiency

Exclusion criteria

Exclusion Criteria:

  • adrenal insufficiency due to adrenocortical carcinoma
  • AI due to long-term pharmacological glucocorticoid treatment
  • glucocortiocid doses above 7.5 mg prednisolone equivalent for other reasons than AI
05

Study design

Observational model
Defined population
Time perspective
Other
06

Study locations

2 sites
  • Dept of Medicine, Gastroenterology, Hepatology and Endocrinology, Charité Campus Mitte, Charité, University Medicine Berlin
    Berlin, D-10117, Germany
  • University of Wuerzburg, Dept of Medicine - Endocrine and Diabetes unit
    Wuerzburg, D-97080, Germany
07

References and documents

Publications

  • Hahner S, Loeffler M, Fassnacht M, Weismann D, Koschker AC, Quinkler M, Decker O, Arlt W, Allolio B. Impaired subjective health status in 256 patients with adrenal insufficiency on standard therapy based on cross-sectional analysis. J Clin Endocrinol Metab. 2007 Oct;92(10):3912-22. doi: 10.1210/jc.2007-0685. Epub 2007 Aug 7. PubMed 17684047 ↗
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 7, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00444119
Lead sponsor
University of Wuerzburg
First posted
Mar 7, 2007
Start date
May 2004
Completion
Apr 2005
Last update
Mar 7, 2007

Study contacts

Bruno Allolio, MD
principal investigator · University of Wuerzburg
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2007. You cannot join it, but the record below documents what was studied.

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