A Phase 4 interventional study of long-term intensive exercise in Rheumatoid Arthritis, sponsored by Leiden University Medical Center. Status unknown. Open to participants aged 17 Years to 70 Years. Per ClinicalTrials.gov, last updated 2007-02-13.
Sponsored by Leiden University Medical Center · Phase 4, Interventional, and Treatment
Aim of the study was to investigate the effectiveness (functional ability and physical capacity) and safety (disease activity and damage of the joints) of long-term high-intensity weight-bearing exercises in patients with rheumatoid arthritis (RA).The training proved to be safe and effective.
The 300 patients with RA were randomized into two groups; exercise group and usual care group. The patients who participated in the 2 years intensive exercise training (2 times a week, training duration 65 minutes) improved their functional capacity and functional ability without detrimental effects on the large joints damage or on disease activity. Only patients with excessive large joint damage at baseline were at risk to develop additional damage when participating in intensive weight-bearing exercises. Patients who exercised were able to delay the decrease of bone mineral density of the hips.
3,554 studies on the registry are indexed under Arthritis; 317 are open to participants now.
This study's enrollment of 300 is above the median of 90 across 2,377 interventional studies indexed under Arthritis.
Browse Arthritis studies →Leiden University Medical Center is the lead sponsor of 326 studies on the registry; 106 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
effectiveness:
primary outcome:functional ability;MACTAR;6 months, 12 months, 18 months, 24 months
safety:
damage of the large joints (Larsen score); each year
effectiveness:
muscle strength (strength of extensors of the knee); each 3 months and
aerobic fitness (ergometer); each 3 months
Safety:
disease activity (DAS) each 3 months
No study locations are listed for this record.
This study is status unknown, as verified in Feb 2007. You cannot join it, but the record below documents what was studied.
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Leiden University Medical Center