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CompletedNCT00416156Updated Dec 27, 2006

Effect of Weight Reduction on Inflammatory Markers and Genes Expression in Obese Individuals

An interventional study of Lifestyle modification in Obesity and Inflammation, sponsored by Taichung Veterans General Hospital. Completed at 1 site in Taiwan. Open to participants aged 20 Years to 70 Years. Per ClinicalTrials.gov, last updated 2006-12-27.

Sponsored by Taichung Veterans General Hospital · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
25
Allocation
Non-randomized
Ages
20 Years to 70 Years
Sex
All
01

Study summary

To investigate whether weight reduction by life style modification for 12 weeks will improve circulating inflammatory markers, adipocytokines as well as gene expression of proinflammatory protein obtained from circulating monocytes from obese individuals.

02

Conditions studied

  • Obesity
  • Inflammation

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Keywords

  • Obesity
  • Inflammation
03

In context

Inflammation

3,439 studies on the registry are indexed under Inflammation; 629 are open to participants now.

This study's enrollment of 25 is below the median of 50 across 2,437 interventional studies indexed under Inflammation.

Browse Inflammation studies →

Lead sponsor

Taichung Veterans General Hospital is the lead sponsor of 170 studies on the registry; 37 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Nondiabetes obese individuals with BMI greater than 27 kgs/m2

Exclusion criteria

Exclusion Criteria:

  • Diabetes
  • Abnormal hepatic, renal and cardiac function
05

Study design

Phase
Not applicable
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
25 participants

Interventions

  • BehavioralLifestyle modification
06

What researchers measure

Primary outcomes

  1. Inflammatory responses after weight reduction

Secondary outcomes

  1. BMI

  2. Circulating inflammatory markers

  3. Adipocytokines

  4. Gene Expression from mononuclear cells

07

Study locations

1 site
  • Taichung Veterans General Hospital
    Taichung, Taiwan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 27, 2006, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00416156
Lead sponsor
Taichung Veterans General Hospital
First posted
Dec 27, 2006
Start date
May 2005
Completion
Nov 2005
Last update
Dec 27, 2006

Study contacts

Wayne H Sheu, MD, PhD
principal investigator · Taichung Veterans General Hospital
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2006. You cannot join it, but the record below documents what was studied.

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