A Phase 3 interventional study of Placebo and LX211 in Uveitis, Posterior, Uveitis, Intermediate and Panuveitis, sponsored by Lux Biosciences, Inc.. Completed at 41 sites in 7 countries. Open to participants aged 13 Years and older. Per ClinicalTrials.gov, last updated 2012-06-22.
Sponsored by Lux Biosciences, Inc. · Phase 3, Interventional, and Treatment
The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with clinically quiescent non-infectious uveitis
61 studies on the registry are indexed under Uveitis, Posterior; 4 are open to participants now.
This study's enrollment of 232 is above the median of 37 across 45 interventional studies indexed under Uveitis, Posterior.
Browse Uveitis, Posterior studies →Lux Biosciences, Inc. is the lead sponsor of 7 studies on the registry; none are open to participants now.
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Minimum prescribed therapy upon enrollment is one or more of the following:
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Drug: Placebo
Drug: LX211
Drug: LX211
Drug: LX211
recurrence of ocular inflammation
Time frame: 26 weeks
BCVA
Time frame: 26 weeks
systemic corticosteroid usage
Time frame: 26 weeks
This study is completed, as verified in Jun 2012. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Voclosporin
Lux Biosciences, Inc.