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TerminatedNCT00355017Updated Oct 18, 2006

BNP Guided Care in Addition to Multidisciplinary Care

An interventional study of BNP-guided care in addition to multidisciplinary management in Decompensated Heart Failure, sponsored by Medical University of Vienna. Terminated. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2006-10-18.

Sponsored by Medical University of Vienna · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Allocation
Randomized
Ages
19 Years and older
Sex
All
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Study summary

HF is associated with repeated hospitalisations and poor prognosis.The aim of this study is to investigate whether BNP-guided care (BGC) in addition to multidisciplinary management(MM) improves outcome compared to HNC alone or usual care (UC) for decompensated HF patients after discharge.

Patients hospitalised with cardiac decompensation in 9 Viennese hospitals are randomised to BGC, MM alone, or UC. MM includes 2 consultations of a heart failure (HF) specialist 10 days and 2 months after discharge for recommending medical optimisation and care by a specialised HF nurse including 4 home visits and telephone contact. In addition, BGC includes intensified increase of medical treatment during repeated follow-up visits in a HF clinic in patients with an Nt-BNP level above 2200pg/ml at discharge.

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Conditions studied

  • Decompensated Heart Failure

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03

In context

Heart Failure

5,697 studies on the registry are indexed under Heart Failure; 1,219 are open to participants now.

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Lead sponsor

Medical University of Vienna is the lead sponsor of 1,076 studies on the registry; 177 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Clinical signs and symptoms of cardiac decompensation during the present hospitalisation
  2. NYHA class III or IV at time of admission
  3. Cardiothoracic ratio > 0.5, and/or left ventricular ejection fraction \<40% documented by echocardiography

Exclusion criteria

Exclusion Criteria:

-

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Study design

Phase
Not applicable
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)

Interventions

  • ProcedureBNP-guided care in addition to multidisciplinary management
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What researchers measure

Primary outcomes

  1. Heart failure rehospitalisation rate;

  2. combined endpoint death or heart failure rehospitalisation;

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Berger R, Moertl D, Peter S, Ahmadi R, Huelsmann M, Yamuti S, Wagner B, Pacher R. N-terminal pro-B-type natriuretic peptide-guided, intensive patient management in addition to multidisciplinary care in chronic heart failure a 3-arm, prospective, randomized pilot study. J Am Coll Cardiol. 2010 Feb 16;55(7):645-53. doi: 10.1016/j.jacc.2009.08.078. PubMed 20170790 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 18, 2006, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00355017
Lead sponsor
Medical University of Vienna
First posted
Jul 20, 2006
Start date
Sep 2003
Completion
Sep 2005
Last update
Oct 18, 2006

Study contacts

Richard Pacher, MD
principal investigator · Medical University of Vienna
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Jul 2006. You cannot join it, but the record below documents what was studied.

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