CClinicalTrials.gg
CompletedNCT00350935Updated Jun 28, 2010

Attention and Visual Perception in Schizophrenia: A Functional Magnetic Resonance Imaging (fMRI) Study

An observational study in Schizophrenia, sponsored by University Hospital, Strasbourg, France. Completed at 1 site in France. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2010-06-28.

Sponsored by University Hospital, Strasbourg, France · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
52
Ages
18 Years to 50 Years
Sex
All
01

Study summary

The main objective of the study is to contribute to a better understanding of the physiopathology of schizophrenia, by studying causal relationships between cognitive deficits and the neurobiological basis for these deficits. Processing visual information involves both automatic grouping processes and control processes. Automatic grouping processes allow the building of a global configuration from local contour information. It is necessary in order to recognize objects. Control processes allow tending to and prioritizing information parts. The paradigm the investigators use allows to dissociate these processes, and is used in order to characterize the impairments observed in patients with schizophrenia. It is adapted to fMRI in order to explore the neurobiological basis of the deficits. The investigators will examine whether functional disconnectivity between activated areas subtend the impairments observed in patients.

02

Conditions studied

  • Schizophrenia

Browse trials for

Keywords

  • fMRI
  • Visual perception
  • Attention
03

In context

Schizophrenia

3,471 studies on the registry are indexed under Schizophrenia; 472 are open to participants now.

This study's planned enrollment of 52 is below the median of 178 across 491 observational studies indexed under Schizophrenia.

Browse Schizophrenia studies →

Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 966 studies on the registry; 342 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Primary care clinic, residents of Strasbourg

Inclusion criteria

  • Patients with schizophrenia (DSM-IV criteria)
  • Healthy controls matched with patients on age, sex and education level
  • Ages 18 to 50
  • Signed informed consent
  • Right-handed

Exclusion criteria

Exclusion Criteria:

  • No severe somatic illness
  • No invalidating sensory disease
  • No drug abuse, as defined by DSM-IV criteria
  • No general anaesthesia in the past 3 months
  • No intake of drugs affecting the CNS, except for patients
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
52 participants (estimated)

Groups and cohorts

  • Healthy volunteers

    Healthy controls

    Procedure: fMRI

  • Patients

    Patients with schizophrenia

    Procedure: fMRI

Interventions

  • ProcedurefMRI

    One 30 minute session

06

Study locations

1 site
  • Inserm U666 - Département de Psychiatrie, Hôpitaux Universitaires de Strasbourg
    Strasbourg, 67091, France
07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 28, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00350935
Lead sponsor
University Hospital, Strasbourg, France
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France, Centre National de la Recherche Scientifique, France, Région Alsace, Faculté de Médecine de Strasbourg
First posted
Jul 11, 2006
Start date
Sep 2006
Completion
Apr 2009
Last update
Jun 28, 2010

Study contacts

Anne Giersch, MD
principal investigator · Institut National de la Santé Et de la Recherche Médicale, France
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2010. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion