Safety Study in Retinal Transplantation for Dry Age Related Macular Degeneration.

• The subject must have decreased central visual acuity of 20/200 or worse in one eye by ETDRS vision testing for a duration of at least one year in the operated eye and have the diagnosis of age related macular degeneration; vision in the nonoperated eye must be better than the operated eye. Vision in the operated eye cannot be better than 20/200.
• Subject is older than 55 years of age
• Patient is willing to return for follow-up visits
• Patient has signed informed consent for retinal transplantation
• Patient has undergone microperimetry and Goldmann visual field testing.

Exclusion Criteria:

• Patient having a central visual acuity of better than 20/200 in one eye by ETDRS or vision worse than 20/200 in one eye by ETDRS for a duration of less than one year
• Unwilling to sign an informed consent
• Patient under 55 years of age
• Patient having medical problems that are contraindicatory for short-term anesthesia
• Patient unwilling to return for follow-up visits
• The patient has been determined to be pregnant by patient history or by pregnancy testing in women of childbearing potential
• Features of any condition other than age-related macular degeneration in the study eye (such as pathologic myopia or presumed ocular histoplasmosis) associated with choroidal neovascularization
• Any significant ocular disease (other than choroidal neovascularization) that has compromised or could compromise vision in the study eye and confound analysis of the primary outcome.
• Inability to obtain photographs to document choroidal neovascularization, including difficulty with venous access
• History of choroidal neovascularization in the study eye
• Participating in another ophthalmic clinical trial or use of any other investigational new drugs within 12 weeks before the start of study treatment
• Prior photodynamic therapy or Macugen therapy for choroidal neovascularization
• Patient who has a history of uveitis, Coat's disease, diabetic retinopathy, glaucoma, or a cataract that prevents visualization of the posterior pole