An observational study in Human Immunodeficiency Virus, sponsored by Canadian Immunodeficiency Research Collaborative. Completed. Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2012-06-05.
Sponsored by Canadian Immunodeficiency Research Collaborative · Observational
To further investigate differences in the immunologic function of various lymphocyte subsets in HIV-infected patients who are treated early in their infection and during the chronic phase of the infection. Studies will also be done to further delineate the various antigen-specific and innate immune responses including characterization of soluble factors associated with primary HIV infection.
Primary HIV-1 infected and chronically infected individuals will be recruited and leukapheresis will be performed. This one year study requires that patients be apheresed once before initiating therapy and on two other occasions (at month 6 and month 12) after suppression of plasma viremia. Peripheral blood mononuclear cells will be isolated by sodium diatrizoate density centrifugation and subjected to immunologic and virologic studies.
2,040 studies on the registry are indexed under Acquired Immunodeficiency Syndrome; 272 are open to participants now.
This study's enrollment of 220 is close to the median of 236 across 355 observational studies indexed under Acquired Immunodeficiency Syndrome.
Browse Acquired Immunodeficiency Syndrome studies →Canadian Immunodeficiency Research Collaborative is the lead sponsor of 8 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
HIV-infected adults who have a positive ELISA and a confirmatory western blot HIV test.
Exclusion Criteria:
pack of cells as per protocol
No study locations are listed for this record.
This study is completed, as verified in Jun 2012. You cannot join it, but the record below documents what was studied.
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Acquired Immunodeficiency Syndrome→
Canadian Immunodeficiency Research Collaborative