An interventional study of Peer-led Dynamic Choice HIV Prevention (DCP) intervention in HIV/AIDS and HIV/AIDS Prevention, sponsored by University of California, San Francisco. Not yet recruiting at 1 site in Uganda. Open to female participants aged 15 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-02.
Sponsored by University of California, San Francisco · Not applicable, Interventional, and Prevention
This Hybrid Type 1 cluster randomized trial will test the Peer-led Dynamic Choice HIV Prevention (DCP) intervention compared to standard of care.
This study will test a Peer-led Dynamic Choice HIV Prevention intervention tailored to women at elevated risk of HIV exposure in Western and South-Central Uganda. The investigators will conduct a cluster randomized trial to test the effectiveness and implementation outcomes of a Peer-led Dynamic Choice HIV Prevention intervention for women.
Exclusion Criteria:
Participants in the experimental arm will receive the Peer-led Dynamic Choice HIV Prevention intervention.
Other: Peer-led Dynamic Choice HIV Prevention (DCP) intervention
Participants in the standard of care arm will receive brief education on HIV prevention and will be referred to the nearby health facility for HIV prevention services per national guidelines.
The intervention consists of peer mentor training on patient-centered choice counseling and Peer-led DCP services, and will be delivered by the peer mentor with remote clinician support: 1) HIV prevention product choice, with the option to switch over time, 2) HIV testing, 3) Low-barrier PEP, 4) STI integration, 5) Travel kit, and 6) Phone/SMS contact and peer support.
Biomedical HIV prevention coverage
Percentage of follow-up time that a participant uses a biomedical HIV prevention product.
Time frame: 48 weeks
Biomedical HIV prevention coverage
Percentage of follow-up time that a participant uses a biomedical HIV prevention product.
Time frame: 96 weeks
Plan to share: Yes — Select de-identified data will be shared with the NIMH Data Archive.
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This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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University of California, San Francisco