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CompletedNCT00331240Updated May 12, 2014

24-Hour Intraocular Pressure (IOP) Control With Travoprost/Timolol Fixed Combination

A Phase 3 interventional study of travoprost/timolol fixed combination and placebo (artificial tears) in Primary Open Angle Glaucoma and Exfoliation Syndrome, sponsored by Aristotle University Of Thessaloniki. Completed at 1 site in Greece. Open to participants aged 29 Years to 80 Years. Per ClinicalTrials.gov, last updated 2014-05-12.

Sponsored by Aristotle University Of Thessaloniki · Phase 3, Interventional, and Treatment

Phase
Phase 3
Study type
Interventional
Enrollment
32
Allocation
Randomized
Ages
29 Years to 80 Years
Sex
All
01

Study summary

The purpose of this study is to compare the short-term (8 week) mean 24-hour intraocular pressure control and safety of TravTim fixed combination given once in the evening with placebo once in the morning versus TravTim given once in the morning with placebo once in the evening in patients with open-angle glaucoma.

02

Conditions studied

  • Primary Open Angle Glaucoma
  • Exfoliation Syndrome
03

In context

Glaucoma, Open-Angle

929 studies on the registry are indexed under Glaucoma, Open-Angle; 122 are open to participants now.

This study's enrollment of 32 is below the median of 80 across 700 interventional studies indexed under Glaucoma, Open-Angle.

Browse Glaucoma, Open-Angle studies →

Lead sponsor

Aristotle University Of Thessaloniki is the lead sponsor of 274 studies on the registry; 56 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
29 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • POAG
  • Exfoliation syndrome

Exclusion criteria

Exclusion Criteria:

  • Advanced glaucoma
05

Study design

Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Double
Enrollment
32 participants

Interventions

  • Drugtravoprost/timolol fixed combination
  • Drugplacebo (artificial tears)
06

Study locations

1 site
  • Glaucoma Unit, A University Dept of Ophthalmology, AHEPA Hospital
    Thessaloniki, 546 36, Greece
07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 12, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00331240
Lead sponsor
Aristotle University Of Thessaloniki
Responsible party
AGP Konstas (Professor in Ophthalmology, Aristotle University Of Thessaloniki) — Principal investigator
First posted
May 29, 2006
Start date
Mar 2006
Primary completion
Jan 2007
Completion
Feb 2007
Last update
May 12, 2014

Study contacts

AGP Konstas, MD, PhD
principal investigator · Glaucoma Unit, A University Dept of Ophthalmology, AHEPA Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2014. You cannot join it, but the record below documents what was studied.

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