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CompletedNCT00307996Updated Mar 28, 2006

The Effect of CoQ10 Administration on Hemodialysis Patients

A Phase 4 interventional study of Coenzyme Q10 (drug) in Chronic Renal Failure and Hemodialysis, sponsored by University of Shizuoka. Completed at 1 site in Japan. Open to participants aged 0 Years to 85 Years. Per ClinicalTrials.gov, last updated 2006-03-28.

Sponsored by University of Shizuoka · Phase 4, Interventional, and Treatment

Phase
Phase 4
Study type
Interventional
Enrollment
40
Allocation
Non-randomized
Ages
0 Years to 85 Years
Sex
All
01

Study summary

The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.

Read the detailed description

Oxidative stress has been recognized as a potential risk factor for such complications as atherosclerosis in hemodialysis patients. This study investigates whether CoQ10 administration is effective for protecting oxidative stress in hemodialysis patients. The subjects were recruited from day-time hemodialysis patients in Iwata City Hospital. 100 mg CoQ10 was administered every HD for 6 months. Several oxidative and antioxidative markers were measured in plasma at pre, 1, 3, 6 months and after washout.

02

Conditions studied

  • Chronic Renal Failure
  • Hemodialysis

Keywords

  • CoQ10
  • hemodialysis
  • oxidative marker
  • antioxidant
03

In context

Kidney Failure, Chronic

2,085 studies on the registry are indexed under Kidney Failure, Chronic; 260 are open to participants now.

This study's enrollment of 40 is below the median of 55 across 1,557 interventional studies indexed under Kidney Failure, Chronic.

Browse Kidney Failure, Chronic studies →

Lead sponsor

University of Shizuoka is the lead sponsor of 11 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
0 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • hemodialysis for at least 6 months

Exclusion criteria

Exclusion Criteria:

  • none
05

Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
40 participants

Interventions

  • DrugCoenzyme Q10 (drug)
06

What researchers measure

Primary outcomes

  1. Oxidative protein concentration at 6 month

  2. Antioxidant capacity at 6 month

07

Study locations

1 site
  • Iwata City Hospital
    Iwata, Shizuoka 438-8550, Japan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 28, 2006, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00307996
Lead sponsor
University of Shizuoka
First posted
Mar 28, 2006
Start date
Mar 2004
Completion
Dec 2004
Last update
Mar 28, 2006

Study contacts

Hiromichi Kumagai, MD
study chair · University of Shizuoka
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2006. You cannot join it, but the record below documents what was studied.

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